Mesenchymal Stem Cells Expressing eNOS and a Cav1 Mutant Inhibit Vascular Smooth Muscle Cell Proliferation in a Rat Model of Pulmonary Hypertension.

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作者： Haiying,Chen ^[1] ; Hongli,Yang ^[2] ; Hongmei,Yue ^[3] ; Pádraig Michael,Strappe ^[4] ; Peng,Xia ^[5] ; Li,Pan ^[2] ; Yingxin,Zhang ^[2] ; Shoudong,Chai ^[6] ; Shuangfeng,Chen ^[2] ; Longle,Ma ^[5] ; Lexin,Wang ^[7]

作者单位： Central Laboratory, and Key Laboratory of Oral and Maxillofacial-Head and Neck Medical Biology, Liaocheng People's Hospital, Liaocheng, China; Liaocheng People's Hospital and Clinical School of Taishan Medical University, Liaocheng, China. ^[1] Central Laboratory, and Key Laboratory of Oral and Maxillofacial-Head and Neck Medical Biology, Liaocheng People's Hospital, Liaocheng, China. ^[2] Liaocheng People's Hospital and Clinical School of Taishan Medical University, Liaocheng, China. ^[3] School of Biomedical Sciences, Charles Sturt University, Wagga Wagga, NSW, Australia. ^[4] Department of Cardiology, Liaocheng People's Hospital and Affiliated Liaocheng People's Hospital of Shandong University, Liaocheng, China. ^[5] Department of Cardiac Surgery, Liaocheng People's Hospital and Affiliated Liaocheng People's Hospital of Shandong University, Liaocheng, China. ^[6] Department of Cardiology, Liaocheng People's Hospital and Affiliated Liaocheng People's Hospital of Shandong University, Liaocheng, China; School of Biomedical Sciences, Charles Sturt University, Wagga Wagga, NSW, Australia. Electronic address: lwang@csu.edu.au. ^[7]

关键词 Bone marrow-derived mesenchymal stem cells Caveolin-1 Endothelial nitric oxide synthase Kruppel-like factor 4 Pulmonary arterial hypertension Ventricular function