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Protein-RNA Networks Regulated by Normal and ALS-Associated Mutant HNRNPA2B1 in the Nervous System.

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第一作者： Fernando J,Martinez

第一单位： Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Stem Cell Program and Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA.

作者： Fernando J,Martinez ^[1] ; Gabriel A,Pratt ^[2] ; Eric L,Van Nostrand ^[1] ; Ranjan,Batra ^[1] ; Stephanie C,Huelga ^[1] ; Katannya,Kapeli ^[3] ; Peter,Freese ^[4] ; Seung J,Chun ^[5] ; Karen,Ling ^[5] ; Chelsea,Gelboin-Burkhart ^[1] ; Layla,Fijany ^[1] ; Harrison C,Wang ^[1] ; Julia K,Nussbacher ^[1] ; Sara M,Broski ^[6] ; Hong Joo,Kim ^[7] ; Rea,Lardelli ^[8] ; Balaji,Sundararaman ^[1] ; John P,Donohue ^[9] ; Ashkan,Javaherian ^[6] ; Jens,Lykke-Andersen ^[8] ; Steven,Finkbeiner ^[10] ; C Frank,Bennett ^[5] ; Manuel,Ares ^[9] ; Christopher B,Burge ^[4] ; J Paul,Taylor ^[7] ; Frank,Rigo ^[5] ; Gene W,Yeo ^[11]

作者单位： Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Stem Cell Program and Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA. ^[1] Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Stem Cell Program and Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Department of Bioinformatics and Systems Biology, University of California, San Diego, La Jolla, CA 92093, USA. ^[2] Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Stem Cell Program and Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore. ^[3] Department of Biology, MIT, Cambridge, MA 02139, USA. ^[4] Ionis Pharmaceuticals, Carlsbad, CA 92010, USA. ^[5] Taube/Koret Center for Neurodegenerative Disease Research, Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA. ^[6] Howard Hughes Medical Institute, Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. ^[7] Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA. ^[8] Department of Molecular, Cell, and Developmental Biology, Sinsheimer Labs, University of California, Santa Cruz, Santa Cruz, CA 95064, USA. ^[9] Taube/Koret Center for Neurodegenerative Disease Research, Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA; Departments of Neurology and Physiology, University of California, San Francisco, San Francisco, CA 94107, USA. ^[10] Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Stem Cell Program and Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Department of Bioinformatics and Systems Biology, University of California, San Diego, La Jolla, CA 92093, USA; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore; Molecular Engineering Laboratory, A(∗)STAR, Singapore 138673, Singapore. Electronic address: geneyeo@ucsd.edu. ^[11]