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Autophagy induced by AXL receptor tyrosine kinase alleviates acute liver injury via inhibition of NLRP3 inflammasome activation in mice.

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第一作者： Jihye,Han

第一单位： a Department of Biotechnology , College of Life Sciences and Biotechnology, Korea University , Seoul , Korea.

作者： Jihye,Han ^[1] ; Joonbeom,Bae ^[1] ; Chang-Yong,Choi ^[1] ; Sang-Pil,Choi ^[1] ; Hyung-Sik,Kang ^[2] ; Eun-Kyeong,Jo ^[3] ; Jongsun,Park ^[4] ; Young Sik,Lee ^[1] ; Hyun-Seuk,Moon ^[1] ; Chung-Gyu,Park ^[5] ; Myung-Shik,Lee ^[6] ; Taehoon,Chun ^[1]

作者单位： a Department of Biotechnology , College of Life Sciences and Biotechnology, Korea University , Seoul , Korea. ^[1] b School of Biological Sciences and Technology, Biotechnology Research Institute, Chonnam National University , Kwangju , Korea. ^[2] c Infection Signaling Network Research Center , Department of Microbiology , College of Medicine, Chungnam National University , Daejeon , Korea. ^[3] d Department of Pharmacology , Metabolic Diseases and Cell Signaling Laboratory, Research Institute for Medical Sciences, College of Medicine, Chungnam National University , Daejeon , Korea. ^[4] e Department of Microbiology and Immunology , Seoul National University College of Medicine , Seoul , Korea. ^[5] f Severance Biomedical Science Institute , Department of Internal Medicine , College of Medicine, Yonsei University , Seoul , Korea. ^[6]

关键词 AXL receptor tyrosine kinase NLRP3 inflammasome autophagy hepatic inflammation macrophage