Heterogeneity of Acquired Resistance to Anti-EGFR Monoclonal Antibodies in Patients with Metastatic Colorectal Cancer.

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作者： Filippo,Pietrantonio ^[1] ; Claudio,Vernieri ^[2] ; Giulia,Siravegna ^[3] ; Alessia,Mennitto ^[4] ; Rosa,Berenato ^[5] ; Federica,Perrone ^[2] ; Annunziata,Gloghini ^[2] ; Elena,Tamborini ^[6] ; Sara,Lonardi ^[6] ; Federica,Morano ^[6] ; Benedetta,Picciani ^[7] ; Adele,Busico ^[2] ; Chiara Costanza,Volpi ^[6] ; Antonia,Martinetti ^[6] ; Francesca,Battaglin ^[6] ; Ilaria,Bossi ^[2] ; Alessio,Pellegrinelli ^[6] ; Massimo,Milione ^[2] ; Chiara,Cremolini ^[6] ; Maria,Di Bartolomeo ^[6] ; Alberto,Bardelli ^[8] ; Filippo,de Braud ^[9]

作者单位： Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. filippo.pietrantonio@istitutotumori.mi.it. ^[1] Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. ^[2] Istituto FIRC di Oncologia Molecolare, Milan, Italy. ^[3] Department of Oncology, University of Torino, Candiolo, Torino, Italy. ^[4] Candiolo Cancer Institute-FPO, IRCCS, Candiolo, Torino, Italy. ^[5] Department of Diagnostic Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. ^[6] Oncologia Medica 1, Istituto Oncologico Veneto-IRCCS, Padova, Italy. ^[7] Polo Oncologico, Azienda Ospedaliero-Universitaria Pisana, Istituto Toscano Tumori, Pisa, Italy. ^[8] University of Pisa, Pisa, Italy. ^[9] Department of Oncology, University of Milan, Milan, Italy. ^[10]