Sirt3 deficiency exacerbates diabetic cardiac dysfunction: Role of Foxo3A-Parkin-mediated mitophagy.

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第一作者： Wenjun,Yu

第一单位： Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China; Department of Cardiology, 306th Hospital of CPLA, Beijing 100101, China; Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.

作者： Wenjun,Yu ^[1] ; Beilei,Gao ^[2] ; Na,Li ^[3] ; Jiaxing,Wang ^[4] ; Cuiting,Qiu ^[5] ; Guoyong,Zhang ^[2] ; Min,Liu ^[5] ; Rongqing,Zhang ^[5] ; Congye,Li ^[5] ; Gang,Ji ^[6] ; Yingmei,Zhang ^[7]

作者单位： Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China; Department of Cardiology, 306th Hospital of CPLA, Beijing 100101, China; Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China. ^[1] Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China; Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China. ^[2] Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China; Department of Cardiology, Yuncheng Central Hospital, Yuncheng 044000, Shanxi Province, China. ^[3] Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China; Department of ICU, 309th Hospital of CPLA, Beijing 100092, China. ^[4] Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China. ^[5] Department of Digestive Diseases, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China. Electronic address: jigang@fmmu.edu.cn. ^[6] Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China; Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China. Electronic address: zhangym197951@126.com. ^[7]

关键词 Cardiac function Foxo3A Mitophagy Parkin Sirt3 Streptozotocin

主题词动物(Animals);细胞凋亡(Apoptosis);糖尿病心肌病(Diabetic Cardiomyopathies);疾病模型, 动物(Disease Models, Animal);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);线粒体, 心脏(Mitochondria, Heart);肌细胞, 心脏(Myocytes, Cardiac);信号传导(Signal Transduction);抗衰老酶3(Sirtuin 3);泛素蛋白连接酶类(Ubiquitin-Protein Ligases)

DOI 10.1016/j.bbadis.2016.10.021

PMID 27794418

发布时间 2022-04-10

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Biochimica et biophysica acta. Molecular basis of disease

2017年1863卷8期

1973-1983页

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Sirt3 deficiency exacerbates diabetic cardiac dysfunction: Role of Foxo3A-Parkin-mediated mitophagy.

Biochimica et biophysica acta. Molecular basis of disease

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Biochimica et biophysica acta. Molecular basis of disease

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Sirt3 deficiency exacerbates diabetic cardiac dysfunction: Role of Foxo3A-Parkin-mediated mitophagy.

Biochimica et biophysica acta. Molecular basis of disease

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Biochimica et biophysica acta. Molecular basis of disease

相关期刊

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