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Structural basis for DNA recognition by STAT6.

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第一作者： Jing,Li

第一单位： National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.;University of Chinese Academy of Sciences, Beijing 100049, China.

作者： Jing,Li ^[1] ; Jose Pindado,Rodriguez ^[2] ; Fengfeng,Niu ^[3] ; Mengchen,Pu ^[3] ; Jinan,Wang ^[4] ; Li-Wei,Hung ^[5] ; Qiang,Shao ^[4] ; Yanping,Zhu ^[3] ; Wei,Ding ^[3] ; Yanqing,Liu ^[3] ; Yurong,Da ^[6] ; Zhi,Yao ^[6] ; Jie,Yang ^[6] ; Yongfang,Zhao ^[3] ; Gong-Hong,Wei ^[7] ; Genhong,Cheng ^[2] ; Zhi-Jie,Liu ^[8] ; Songying,Ouyang ^[9]

作者单位： National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.;University of Chinese Academy of Sciences, Beijing 100049, China. ^[1] Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA 90095. ^[2] National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China. ^[3] Drug Discovery and Design Center, Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. ^[4] Physics Division, Los Alamos National Laboratory, Los Alamos, NM 87545. ^[5] Department of Immunology, Tianjin Medical University, Tianjin 300070, China. ^[6] Biocenter Oulu and Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu 90220, Finland. ^[7] National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.;Department of Immunology, Tianjin Medical University, Tianjin 300070, China.;iHuman Institute, Shanghai Tech University, Shanghai 201210, China.;Institute of Molecular and Clinical Medicine, Kunming Medical University, Kunming 650500, China. ^[8] National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; ouyangsy@ibp.ac.cn.;Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA 90095. ^[9]

关键词 JAK-STAT pathway N4 site DNA recognition STAT6 antiviral innate immunity crystal structure