Deletion of the Imprinted Gene Grb10 Promotes Hematopoietic Stem Cell Self-Renewal and Regeneration.

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第一作者： Xiao,Yan

第一单位： Division of Hematology/Oncology, Department of Medicine, UCLA, Los Angeles, CA 90095, USA; Department of Molecular and Medical Pharmacology, UCLA, Los Angeles, CA 90095, USA.

作者： Xiao,Yan ^[1] ; Heather A,Himburg ^[2] ; Katherine,Pohl ^[2] ; Mamle,Quarmyne ^[2] ; Evelyn,Tran ^[2] ; Yurun,Zhang ^[3] ; Tiancheng,Fang ^[1] ; Jenny,Kan ^[2] ; Nelson J,Chao ^[4] ; Liman,Zhao ^[2] ; Phuong L,Doan ^[4] ; John P,Chute ^[5]

作者单位： Division of Hematology/Oncology, Department of Medicine, UCLA, Los Angeles, CA 90095, USA; Department of Molecular and Medical Pharmacology, UCLA, Los Angeles, CA 90095, USA. ^[1] Division of Hematology/Oncology, Department of Medicine, UCLA, Los Angeles, CA 90095, USA. ^[2] Division of Hematology/Oncology, Department of Medicine, UCLA, Los Angeles, CA 90095, USA; Molecular Biology Institute, UCLA, Los Angeles, CA 90095, USA. ^[3] Division of Hematologic Malignancies and Cellular Therapy, Duke University, Durham, NC 27710, USA. ^[4] Division of Hematology/Oncology, Department of Medicine, UCLA, Los Angeles, CA 90095, USA; Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, UCLA, Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, CA 90095, USA. Electronic address: jchute@mednet.ucla.edu. ^[5]

关键词 adaptor protein hematopoietic stem cells imprinted gene regeneration self-renewal