Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer.-论文-万方医学网

作者： Sylvain,Delaunay ^[1] ; Francesca,Rapino ^[2] ; Lars,Tharun ^[3] ; Zhaoli,Zhou ^[1] ; Lukas,Heukamp ^[2] ; Martin,Termathe ^[3] ; Kateryna,Shostak ^[4] ; Iva,Klevernic ^[1] ; Alexandra,Florin ^[2] ; Hadrien,Desmecht ^[3] ; Christophe J,Desmet ^[4] ; Laurent,Nguyen ^[5] ; Sebastian A,Leidel ^[6] ; Anne E,Willis ^[7] ; Reinhard,Büttner ^[2] ; Alain,Chariot ^[3] ; Pierre,Close ^[7]

作者单位： Laboratory of Cancer Signaling, University of Liège, 4000 Liège, Belgium. ^[1] GIGA-Molecular Biology of Diseases, University of Liège, 4000 Liège, Belgium. ^[2] GIGA-Research, University of Liège, 4000 Liège, Belgium. ^[3] Institute for Pathology, University Hospital Cologne, 50937 Cologne, Germany. ^[4] Max Planck Research Group for RNA Biology, Max Planck Institute for Molecular Biomedicine, 48149 Muenster. ^[5] Faculty of Medicine, University of Muenster, 48129 Muenster, Germany. ^[6] Laboratory of Medical Chemistry, University of Liège, 4000 Liège, Belgium. ^[7] GIGA-Infection, Immunity and Inflammation, University of Liège, 4000 Liège, Belgium. ^[8] GIGA-Neurosiences, University of Liège, 4000 Liège, Belgium. ^[9] Cells-in-Motion Cluster of Excellence, University of Muenster, 48129 Muenster, Germany. ^[10] Medical Research Council Toxicology Unit, Leicester LE1 9HN, England, UK. ^[11] Laboratory of Medical Chemistry, University of Liège, 4000 Liège, Belgium Alain.Chariot@ulg.ac.be Pierre.Close@ulg.ac.be. ^[12] Walloon Excellence in Life Sciences and Biotechnology (WELBIO), 1300 Wavre, Belgium. ^[13] Laboratory of Cancer Signaling, University of Liège, 4000 Liège, Belgium Alain.Chariot@ulg.ac.be Pierre.Close@ulg.ac.be. ^[14]

主题词动物(Animals);乳腺肿瘤(Breast Neoplasms);细胞运动(Cell Movement);染色体蛋白质类, 非组蛋白(Chromosomal Proteins, Non-Histone);女(雌)性(Female);基因表达谱(Gene Expression Profiling);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);组蛋白酰基转移酶(Histone Acetyltransferases);人类(Humans);淋巴样增强子结合因子1(Lymphoid Enhancer-Binding Factor 1);小鼠(Mice);模型, 生物学(Models, Biological);肿瘤侵润(Neoplasm Invasiveness);肿瘤转移(Neoplasm Metastasis);神经组织蛋白质类(Nerve Tissue Proteins);癌基因蛋白质类(Oncogene Proteins);蛋白质生物合成(Protein Biosynthesis);RNA, 转移(RNA, Transfer);硫脲苷(Thiouridine);增量调节(Up-Regulation)

DOI 10.1084/jem.20160397

PMID 27811057

发布时间 2024-03-27

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Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer.

The Journal of experimental medicine

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Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer.

The Journal of experimental medicine

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The Journal of experimental medicine

相关期刊

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