换一批Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing <i>Npc1l1</i> expression.
第一作者：
Takuya,Kikuchi
第一单位：
Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan.
作者：
关键词
ABCG5/8, adenosine triphosphate-binding cassette transporter G5/G8ALT, alanine aminotransferaseAST, aspartate aminotransferaseAbca1, ATP-binding cassette, sub-family A1Apoa4, apolipoprotein A-IVCREBHCREBH, cyclic AMP-responsive element-binding protein HCholesterolCpt1a, carnitine palmitoyltransferase 1a, liverCyp7a1, cytochrome P450, family 7, subfamily a, polypeptide 1ER, endoplasmic reticulumFGF21, fibroblast growth factor 21FXR, Farnesoid X receptorIntestineLD, lithogenic dietLPL, lipoprotein lipaseLXR, liver X receptorNEFA, non-esterified fatty acidsNPC1L1, Nieman Pick C1-like 1Npc1l1PPARα, proliferator activated receptor alphaRCT, reverse cholesterol transportSREBP, sterol regulatory element-binding proteinShp, small heterodimer partnerSrb1, scavenger receptor class B, member 1Srebf, sterol regulatory element-binding factorTG, triglycerideWT, wild type
医学主题词
ATP结合匣式转运子(ATP-Binding Cassette Transporters);动物(Animals);胆固醇, 膳食(Cholesterol, Dietary);cAMP反应元件结合蛋白质(Cyclic AMP Response Element-Binding Protein);人类(Humans);高胆固醇血症(Hypercholesterolemia);脂蛋白类(Lipoproteins);膜蛋白质类(Membrane Proteins);膜转运蛋白质类(Membrane Transport Proteins);小鼠(Mice)
DOI
10.1016/j.molmet.2016.09.004
PMID
27818935
发布时间
2018-12-02
- 浏览36
Molecular metabolism
2016年5卷11期
1092-1102页
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文
