Heparan Sulfate and Heparin Promote Faithful Prion Replication in Vitro by Binding to Normal and Abnormal Prion Proteins in Protein Misfolding Cyclic Amplification.

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作者： Morikazu,Imamura ^[1] ; Naoko,Tabeta ^[2] ; Nobuko,Kato ^[2] ; Yuichi,Matsuura ^[2] ; Yoshifumi,Iwamaru ^[2] ; Takashi,Yokoyama ^[2] ; Yuichi,Murayama ^[2]

作者单位： From the National Institute of Animal Health, National Agriculture and Food Research Organization (NARO), Tsukuba, Ibaraki 305-0856, Japan imamuram@affrc.go.jp. ^[1] From the National Institute of Animal Health, National Agriculture and Food Research Organization (NARO), Tsukuba, Ibaraki 305-0856, Japan. ^[2]

关键词 baculovirus-recombinant prion protein heparan sulfate heparin prion prion disease protein folding protein misfolding cyclic amplification

主题词动物(Animals);肝素(Heparin);硫酸乙酰肝素(Heparitin Sulfate);小鼠(Mice);蛋白质折叠(Protein Folding)

DOI 10.1074/jbc.M116.745851

PMID 27821590

发布时间 2021-02-09

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