首页> Journal of applied genetics> The effect of UGT1A9, CYP2B6 and CYP2C9 genes polymorphism on individual differences in propofol pharmacokinetics among Polish patients undergoing general anaesthesia.

The effect of UGT1A9, CYP2B6 and CYP2C9 genes polymorphism on individual differences in propofol pharmacokinetics among Polish patients undergoing general anaesthesia.

导出 OA

翻译打印收藏纠错

第一作者： Adam,Mikstacki

第一单位： Department of Anaesthesiology and Intensive Therapy, Regional Hospital, Juraszow 7/19, 60-479, Poznan, Poland.

作者： Adam,Mikstacki ^[1] ; Oliwia,Zakerska-Banaszak ^[2] ; Marzena,Skrzypczak-Zielinska ^[2] ; Barbara,Tamowicz ^[1] ; Michał,Prendecki ^[3] ; Jolanta,Dorszewska ^[3] ; Marta,Molinska-Glura ^[4] ; Malgorzata,Waszak ^[5] ; Ryszard,Slomski ^[6]

作者单位： Department of Anaesthesiology and Intensive Therapy, Regional Hospital, Juraszow 7/19, 60-479, Poznan, Poland. ^[1] Institute of Human Genetics, Polish Academy of Sciences, Strzeszynska 32, 60-479, Poznan, Poland. ^[2] Laboratory of Neurobiology, Poznan University of Medical Sciences, Przybyszewskiego 49, 60-355, Poznan, Poland. ^[3] Department of Computer Science and Statistics, Poznan University of Medical Sciences, Dabrowskiego 79, 60-529, Poznan, Poland. ^[4] Department of Functional Anatomy, University School of Physical Education in Poznan, Krolowej Jadwigi 27/39, 61-871, Poznan, Poland. ^[5] Institute of Human Genetics, Polish Academy of Sciences, Strzeszynska 32, 60-479, Poznan, Poland. slomski@up.poznan.pl.;Department of Biochemistry and Biotechnology, University of Life Sciences, Dojazd 11, 60-632, Poznan, Poland. slomski@up.poznan.pl. ^[6]

关键词 General anaesthesia Genotyping Individual response Pharmacokinetics Propofol