换一批
换一批MCAM/CD146 promotes tamoxifen resistance in breast cancer cells through induction of epithelial-mesenchymal transition, decreased ERα expression and AKT activation.
第一作者：
Yuan-Ke,Liang
第一单位：
The Breast Center, Cancer Hospital of Shantou University Medical College, 7 Raoping Road, Shantou, China; ChangJiang Scholar's Laboratory of Shantou University Medical College, 22 Xinling Road, Shantou, China; Department of Medical Oncology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
作者：
主题词
抗肿瘤药, 激素(Antineoplastic Agents, Hormonal);乳腺肿瘤(Breast Neoplasms);细胞运动(Cell Movement);数据库, 事实型(Databases, Factual);无病生存(Disease-Free Survival);剂量效应关系, 药物(Dose-Response Relationship, Drug);减量调节(Down-Regulation);抗药性, 肿瘤(Drug Resistance, Neoplasm);酶激活(Enzyme Activation);上皮-间质转化(Epithelial-Mesenchymal Transition);雌激素拮抗剂(Estrogen Antagonists);雌激素受体α(Estrogen Receptor alpha);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);Kaplan-Meiers评估(Kaplan-Meier Estimate);肿瘤转移(Neoplasm Metastasis);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);信号传导(Signal Transduction);他莫昔芬(Tamoxifen);时间因素(Time Factors);增量调节(Up-Regulation)
DOI
10.1016/j.canlet.2016.11.004
PMID
27838413
发布时间
2021-08-16
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Cancer letters
65-76页
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