Functional Effect of the Mutations Similar to the Cleavage during Platelet Activation at Integrin β3 Cytoplasmic Tail when Expressed in Mouse Platelets.-论文-万方医学网

第一作者： Xiaofeng,Shi

第一单位： State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Collaborative Innovation Center of Hematology, Sino-French Research Center for Life Sciences and Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.

作者： Xiaofeng,Shi ^[1] ; Jichun,Yang ^[2] ; Xiongying,Cui ^[1] ; Jiansong,Huang ^[1] ; Zhangbiao,Long ^[1] ; Yulan,Zhou ^[3] ; Ping,Liu ^[1] ; Lanlan,Tao ^[1] ; Zheng,Ruan ^[1] ; Bing,Xiao ^[1] ; Wei,Zhang ^[1] ; Dongya,Li ^[1] ; Kesheng,Dai ^[1] ; Jianhua,Mao ^[1] ; Xiaodong,Xi ^[2]

作者单位： State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Collaborative Innovation Center of Hematology, Sino-French Research Center for Life Sciences and Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. ^[1] Department of Hematology, Affiliated Hospital of Jiangsu University, Zhenjiang, China. ^[2] Department of Hematology, Institute of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China. ^[3] Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Key Laboratory of Thrombosis and Hemostasis, Ministry of Health, Suzhou, 215006, China. ^[4]

主题词氨基酸特征结构(Amino Acid Motifs);氨基酸序列(Amino Acid Sequence);动物(Animals);血小板(Blood Platelets);细胞质(Cytoplasm);女(雌)性(Female);纤维蛋白原(Fibrinogen);绿色荧光蛋白质类(Green Fluorescent Proteins);血液流变学(Hemorheology);固定化蛋白质类(Immobilized Proteins);整合素β3(Integrin beta3);小鼠, 近交C57BL(Mice, Inbred C57BL);突变蛋白质类(Mutant Proteins);突变(Mutation);血小板活化(Platelet Activation);血小板黏附(Platelet Adhesiveness);血小板糖蛋白GPⅡb-Ⅲa复合物(Platelet Glycoprotein GPIIb-IIIa Complex);蛋白质结合(Protein Binding);逆转录病毒科(Retroviridae);信号传导(Signal Transduction);溶解度(Solubility);转染(Transfection)

DOI 10.1371/journal.pone.0166136

PMID 27851790

发布时间 2018-11-13

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Functional Effect of the Mutations Similar to the Cleavage during Platelet Activation at Integrin β3 Cytoplasmic Tail when Expressed in Mouse Platelets.

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Functional Effect of the Mutations Similar to the Cleavage during Platelet Activation at Integrin β3 Cytoplasmic Tail when Expressed in Mouse Platelets.

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