Downregulation of estrogen receptor and modulation of growth of breast cancer cell lines mediated by paracrine stromal cell signals.
第一作者:
J,Huang
第一单位:
Department of Medicine, University of Pittsburgh School of Medicine and University of Pittsburgh Cancer Institute, Suite 2.26f Hillman Cancer Center, 5117 Centre Avenue, Pittsburgh, PA, 15213, USA.;School of Medicine, Tsinghua University, Beijing, China.
作者:
医学主题词
抗肿瘤药, 激素(Antineoplastic Agents, Hormonal);乳腺肿瘤(Breast Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);抗药性, 肿瘤(Drug Resistance, Neoplasm);内质网(Endoplasmic Reticulum);雌二醇(Estradiol);雌激素受体α(Estrogen Receptor alpha);外泌体(Exosomes);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);白细胞介素1(Interleukin-1);微RNAs(MicroRNAs);旁分泌细胞细胞间通讯(Paracrine Communication);受体, 雌激素(Receptors, Estrogen);信号传导(Signal Transduction);间质细胞(Stromal Cells)
DOI
10.1007/s10549-016-4052-0
PMID
27853906
发布时间
2018-12-03
基金项目
P30 CA047904/CA/NCI NIH HHS/United States
R01 CA154728/CA/NCI NIH HHS/United States
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