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Hypermutation In Pancreatic Cancer.

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作者: Jeremy L,Humphris [1] ; Ann-Marie,Patch [2] ; Katia,Nones [2] ; Peter J,Bailey [3] ; Amber L,Johns [1] ; Skye,McKay [1] ; David K,Chang [4] ; David K,Miller [5] ; Marina,Pajic [6] ; Karin S,Kassahn [7] ; Michael C J,Quinn [2] ; Timothy J C,Bruxner [8] ; Angelika N,Christ [8] ; Ivon,Harliwong [8] ; Senel,Idrisoglu [8] ; Suzanne,Manning [8] ; Craig,Nourse [9] ; Ehsan,Nourbakhsh [8] ; Andrew,Stone [1] ; Peter J,Wilson [8] ; Matthew,Anderson [8] ; J Lynn,Fink [8] ; Oliver,Holmes [2] ; Stephen,Kazakoff [2] ; Conrad,Leonard [2] ; Felicity,Newell [2] ; Nick,Waddell [8] ; Scott,Wood [2] ; Ronald S,Mead [10] ; Qinying,Xu [2] ; Jianmin,Wu [1] ; Mark,Pinese [1] ; Mark J,Cowley [6] ; Marc D,Jones [11] ; Adnan M,Nagrial [1] ; Venessa T,Chin [1] ; Lorraine A,Chantrill [12] ; Amanda,Mawson [1] ; Angela,Chou [13] ; Christopher J,Scarlett [14] ; Andreia V,Pinho [1] ; Ilse,Rooman [1] ; Marc,Giry-Laterriere [1] ; Jaswinder S,Samra [15] ; James G,Kench [16] ; Neil D,Merrett [17] ; Christopher W,Toon [1] ; Krishna,Epari [18] ; Nam Q,Nguyen [19] ; Andrew,Barbour [20] ; Nikolajs,Zeps [21] ; Nigel B,Jamieson [22] ; Colin J,McKay [23] ; C Ross,Carter [23] ; Euan J,Dickson [23] ; Janet S,Graham [24] ; Fraser,Duthie [25] ; Karin,Oien [25] ; Jane,Hair [26] ; Jennifer P,Morton [27] ; Owen J,Sansom [27] ; Robert,Grützmann [28] ; Ralph H,Hruban [29] ; Anirban,Maitra [29] ; Christine A,Iacobuzio-Donahue [29] ; Richard D,Schulick [30] ; Christopher L,Wolfgang [30] ; Richard A,Morgan [29] ; Rita T,Lawlor [31] ; Borislav,Rusev [31] ; Vincenzo,Corbo [31] ; Roberto,Salvia [31] ; Ivana,Cataldo [31] ; Giampaolo,Tortora [32] ; Margaret A,Tempero [33] ; Australian Pancreatic Cancer Genome Initiative [34] ; Oliver,Hofmann [35] ; James R,Eshleman [29] ; Christian,Pilarsky [36] ; Aldo,Scarpa [31] ; Elizabeth A,Musgrove [37] ; Anthony J,Gill [38] ; John V,Pearson [2] ; Sean M,Grimmond [39] ; Nicola,Waddell [40] ; Andrew V,Biankin [41]
作者单位: The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia. [1] QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia. [2] Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom. [3] Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom; Department of Surgery, Bankstown Hospital, Bankstown, Sydney, New South Wales, Australia; South Western Sydney Clinical School, Faculty of Medicine, University of New South Wales Australia, Liverpool, New South Wales, Australia; West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, United Kingdom. [4] The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia. [5] The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia; St Vincent's Clinical School, Faculty of Medicine, University of New South Wales Australia, Darlinghurst, New South Wales, Australia. [6] Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia; Genetic and Molecular Pathology, Adelaide, South Australia, Australia; School of Biological Sciences, The University of Adelaide, Adelaide, South Australia, Australia. [7] Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia. [8] Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia; St Vincent's Clinical School, Faculty of Medicine, University of New South Wales Australia, Darlinghurst, New South Wales, Australia. [9] The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia; South Eastern Area Laboratory Services Pathology, Prince of Wales Hospital, Randwick, New South Wales, Australia; Sonic Genetics, Douglass Hanly Moir Pathology, New South Wales, Australia. [10] The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom. [11] The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia; Macarthur Cancer Therapy Centre, Campbelltown Hospital, New South Wales, Australia. [12] The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia; Department of Anatomical Pathology, SydPath, St Vincent's Hospital, New South Wales, Australia. [13] The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia; School of Environmental and Life Sciences, University of Newcastle, Ourimbah, New South Wales, Australia. [14] Department of Surgery, Royal North Shore Hospital, Sydney, New South Wales, Australia; University of Sydney, Sydney, New South Wales, Australia. [15] The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia; University of Sydney, Sydney, New South Wales, Australia; Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia. [16] Department of Surgery, Bankstown Hospital, Bankstown, Sydney, New South Wales, Australia; School of Medicine, Western Sydney University, Penrith, New South Wales, Australia. [17] Department of Surgery, Fiona Stanley Hospital, Murdoch, Washington. [18] Department of Gastroenterology, Royal Adelaide Hospital, North Terrace, Adelaide, South Australia, Australia. [19] Department of Surgery, Princess Alexandra Hospital, Woollongabba, Queensland, Australia. [20] School of Surgery, University of Western Australia, Australia and St John of God Pathology, Subiaco, Washington. [21] Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom; West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, United Kingdom; Academic Unit of Surgery, School of Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow Royal Infirmary, Glasgow, United Kingdom. [22] West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, United Kingdom. [23] Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom; Department of Medical Oncology, Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom. [24] Department of Pathology, Southern General Hospital, Greater Glasgow & Clyde National Health Service, Glasgow, United Kingdom. [25] Greater Glasgow and Clyde Bio-repository, Pathology Department, Queen Elizabeth University Hospital, Glasgow, United Kingdom. [26] Cancer Research UK Beatson Institute, Glasgow, United Kingdom; Institute for Cancer Science, University of Glasgow, Glasgow, United Kingdom. [27] Universitätsklinikum Erlangen, Erlangen, Germany. [28] Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, the Johns Hopkins University School of Medicine, Baltimore, Maryland. [29] Department of Surgery, The Sol Goldman Pancreatic Cancer Research Center, the Johns Hopkins University School of Medicine, Baltimore, Maryland. [30] ARC-NET Center for Applied Research on Cancer, University and Hospital Trust of Verona, Verona, Italy; Department of Pathology and Diagnostics, University of Verona, Verona, Italy. [31] Department of Medicine, University and Hospital Trust of Verona, Verona, Italy. [32] Division of Hematology and Oncology, University of California, San Francisco, California. [33] Australian Pancreatic Cancer Genome Initiative. [34] Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom. [35] Universitätsklinikum Erlangen, Department of Surgery, University of Erlangen-Nueremberg, Germany. [36] The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom; St Vincent's Clinical School, Faculty of Medicine, University of New South Wales Australia, Darlinghurst, New South Wales, Australia. [37] The Kinghorn Cancer Centre, Darlinghurst, and the Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia; University of Sydney, Sydney, New South Wales, Australia; Department of Anatomical Pathology, Royal North Shore Hospital, Sydney, New South Wales, Australia. [38] Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia; University of Melbourne Centre for Cancer Research, The University of Melbourne, Melbourne, Victoria, Australia. [39] QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia. Electronic address: nic.waddell@qimrberghofer.edu.au. [40] Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom; Department of Surgery, Bankstown Hospital, Bankstown, Sydney, New South Wales, Australia; South Western Sydney Clinical School, Faculty of Medicine, University of New South Wales Australia, Liverpool, New South Wales, Australia; West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, United Kingdom. Electronic address: andrew.biankin@glasgow.ac.uk. [41]
DOI 10.1053/j.gastro.2016.09.060
PMID 27856273
发布时间 2024-02-10
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