Sesamin inhibits IL-1β-stimulated inflammatory response in human osteoarthritis chondrocytes by activating Nrf2 signaling pathway.
第一作者:
Pengyu,Kong
第一单位:
Department of Orthopedics Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
作者:
主题词
消炎药(Anti-Inflammatory Agents);细胞存活(Cell Survival);细胞, 培养的(Cells, Cultured);软骨细胞(Chondrocytes);地诺前列酮(Dinoprostone);二恶茂类(Dioxoles);剂量效应关系, 药物(Dose-Response Relationship, Drug);血红素加氧酶-1(Heme Oxygenase-1);人类(Humans);白细胞介素1β(Interleukin-1beta);木酚素类(Lignans);基质金属蛋白酶类, 分泌(Matrix Metalloproteinases, Secreted);中年人(Middle Aged);NF-E2相关因子2(NF-E2-Related Factor 2);一氧化氮(Nitric Oxide);骨关节炎, 膝(Osteoarthritis, Knee);磷酰化(Phosphorylation);RNA干扰(RNA Interference);信号传导(Signal Transduction);转录因子RelA(Transcription Factor RelA);转染(Transfection)
DOI
10.18632/oncotarget.13360
PMID
27863411
发布时间
2018-11-13
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Oncotarget
83720-83726页
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