Prostaglandin E<sub>2</sub> Activates YAP and a Positive-Signaling Loop to Promote Colon Regeneration After Colitis but Also Carcinogenesis in Mice.

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第一作者： Han-Byul,Kim

第一单位： Biomedical Science and Engineering Interdisciplinary Program, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, South Korea; National Creative Research Initiatives Center, Department of Biological Sciences, Biomedical Research Center, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, South Korea; Biomedical Research Center, Asan Institute for Life Sciences, Seoul, South Korea.

作者： Han-Byul,Kim ^[1] ; Minchul,Kim ^[2] ; Young-Soo,Park ^[3] ; Intae,Park ^[4] ; Tackhoon,Kim ^[2] ; Sung-Yeun,Yang ^[5] ; Charles J,Cho ^[6] ; DaeHee,Hwang ^[2] ; Jin-Hak,Jung ^[7] ; Sanford D,Markowitz ^[8] ; Sung Wook,Hwang ^[6] ; Suk-Kyun,Yang ^[6] ; Dae-Sik,Lim ^[9] ; Seung-Jae,Myung ^[10]

作者单位： Biomedical Science and Engineering Interdisciplinary Program, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, South Korea; National Creative Research Initiatives Center, Department of Biological Sciences, Biomedical Research Center, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, South Korea; Biomedical Research Center, Asan Institute for Life Sciences, Seoul, South Korea. ^[1] National Creative Research Initiatives Center, Department of Biological Sciences, Biomedical Research Center, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, South Korea. ^[2] Biomedical Research Center, Asan Institute for Life Sciences, Seoul, South Korea; Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea. ^[3] Biomedical Science and Engineering Interdisciplinary Program, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, South Korea; Biomedical Research Center, Asan Institute for Life Sciences, Seoul, South Korea. ^[4] Department of Gastroenterology, Haeundae Paik Hospital, Inje University, Busan, South Korea. ^[5] Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea. ^[6] Biomedical Research Center, Asan Institute for Life Sciences, Seoul, South Korea. ^[7] Department of Medicine and Comprehensive Cancer Center, University Hospitals Case Medical Center and Case Western Reserve University, Cleveland, Ohio. ^[8] National Creative Research Initiatives Center, Department of Biological Sciences, Biomedical Research Center, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, South Korea. Electronic address: daesiklim@kaist.ac.kr. ^[9] Biomedical Research Center, Asan Institute for Life Sciences, Seoul, South Korea; Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea; Department of Convergence Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea. Electronic address: sjmyung@amc.seoul.kr. ^[10]

关键词 Inflammation Mouse Model Tumorigenesis Villus Regeneration