Transforming growth factor-β plays divergent roles in modulating vascular remodeling, inflammation, and pulmonary fibrosis in a murine model of scleroderma.

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作者： Kazuyuki,Tsujino ^[1] ; Nilgun Isik,Reed ^[1] ; Amha,Atakilit ^[1] ; Xin,Ren ^[1] ; Dean,Sheppard ^[2]

作者单位： Department of Medicine, University of California, San Francisco, California. ^[1] Department of Medicine, University of California, San Francisco, California dean.sheppard@ucsf.edu. ^[2]

关键词 fibrosis inflammation systemic sclerosis transforming growth factor-β vasculopathy

主题词肌动蛋白类(Actins);动物(Animals);骨形态发生蛋白受体, Ⅱ型(Bone Morphogenetic Protein Receptors, Type II);疾病模型, 动物(Disease Models, Animal);Fos相关抗原2(Fos-Related Antigen-2);基因缺失(Gene Deletion);粒细胞(Granulocytes);小鼠, 转基因(Mice, Transgenic);肌细胞, 平滑肌(Myocytes, Smooth Muscle);肺炎(Pneumonia);肺泡(Pulmonary Alveoli);肺纤维化(Pulmonary Fibrosis);受体, 转化生长因子β(Receptors, Transforming Growth Factor beta);硬皮病, 系统性(Scleroderma, Systemic);信号传导(Signal Transduction);转化生长因子β(Transforming Growth Factor beta);血管疾病(Vascular Diseases)

DOI 10.1152/ajplung.00428.2016

PMID 27864286

发布时间 2021-12-04

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American journal of physiology. Lung cellular and molecular physiology

2017年312卷1期

L22-L31页

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Transforming growth factor-β plays divergent roles in modulating vascular remodeling, inflammation, and pulmonary fibrosis in a murine model of scleroderma.

American journal of physiology. Lung cellular and molecular physiology

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American journal of physiology. Lung cellular and molecular physiology

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Transforming growth factor-β plays divergent roles in modulating vascular remodeling, inflammation, and pulmonary fibrosis in a murine model of scleroderma.

American journal of physiology. Lung cellular and molecular physiology

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American journal of physiology. Lung cellular and molecular physiology

相关期刊

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