An unconventional interaction between Dis1/TOG and Mal3/EB1 in fission yeast promotes the fidelity of chromosome segregation.

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第一作者： Yuzy,Matsuo

第一单位： Synthetic and Systems Biochemistry of the Microtubule Cytoskeleton Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.

作者： Yuzy,Matsuo ^[1] ; Sebastian P,Maurer ^[2] ; Masashi,Yukawa ^[1] ; Silva,Zakian ^[3] ; Martin R,Singleton ^[4] ; Thomas,Surrey ^[5] ; Takashi,Toda ^[6]

作者单位： Synthetic and Systems Biochemistry of the Microtubule Cytoskeleton Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK. ^[1] Cell Regulation Laboratory, The Francis Crick Institute, 44 Lincoln's Inn Fields, London WC2A 3LY, UK. ^[2] Cell and Developmental Biology, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Dr. Aiguader 88, Barcelona 08003, Spain. ^[3] Universitat Pompeu Fabra (UPF), Barcelona 08002, Spain. ^[4] Hiroshima Research Center for Healthy Aging (HiHA), Department of Molecular Biotechnology, Graduate School of Advanced Science of Matter, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima 739-8530, Japan. ^[5] Structural Biology of Chromosome Segregation Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK. ^[6] Synthetic and Systems Biochemistry of the Microtubule Cytoskeleton Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK Thomas.Surrey@crick.ac.uk takashi-toda@hiroshima-u.ac.jp. ^[7] Cell Regulation Laboratory, The Francis Crick Institute, 44 Lincoln's Inn Fields, London WC2A 3LY, UK Thomas.Surrey@crick.ac.uk takashi-toda@hiroshima-u.ac.jp. ^[8]

关键词 Crystallography EB1 Microtubule polymerase TIRF microscopy TOG XMAP215