Breast Cancer Resistance to Antiestrogens Is Enhanced by Increased ER Degradation and ERBB2 Expression.-论文-万方医学网

第一作者： Tomohiro,Shibata

第一单位： Department of Pharmaceutical Oncology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.

作者： Tomohiro,Shibata ^[1] ; Kosuke,Watari ^[1] ; Hiroto,Izumi ^[2] ; Akihiko,Kawahara ^[3] ; Satoshi,Hattori ^[4] ; Chihiro,Fukumitsu ^[3] ; Yuichi,Murakami ^[5] ; Ryuji,Takahashi ^[6] ; Uhi,Toh ^[7] ; Ken-Ichi,Ito ^[8] ; Shigehiro,Ohdo ^[9] ; Maki,Tanaka ^[10] ; Masayoshi,Kage ^[3] ; Michihiko,Kuwano ^[11] ; Mayumi,Ono ^[12]

作者单位： Department of Pharmaceutical Oncology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan. ^[1] Department of Occupational Pneumology, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Kitakyushu, Japan. ^[2] Department of Diagnostic Pathology, Kurume University Hospital, Kurume, Japan. ^[3] Biostatistics Center, Kurume University, Kurume, Japan. ^[4] Department of Pharmaceutical Oncology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.;Cancer Translational Research Center, St. Mary's Institute of Health Sciences, Kurume, Japan. ^[5] Department of Breast Care Center, Kyushu Medical Center, Fukuoka, Japan. ^[6] Department of Surgery, Kurume University School of Medicine, Kurume, Japan. ^[7] Division of Breast and Endocrine Surgery, Department of Surgery, Shinshu University School of Medicine, Matsumoto, Japan. ^[8] Department of Pharmaceutics, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan. ^[9] Kurume General Hospital, Japan Community Health Care Organization (JCHO), Kurume, Japan. ^[10] Cancer Translational Research Center, St. Mary's Institute of Health Sciences, Kurume, Japan. ^[11] Department of Pharmaceutical Oncology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan. mono@phar.kyushu-u.ac.jp. ^[12]

主题词成年人(Adult);动物(Animals);印迹法, 蛋白质(Blotting, Western);乳腺肿瘤(Breast Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);抗药性, 肿瘤(Drug Resistance, Neoplasm);雌二醇(Estradiol);雌激素受体调节剂(Estrogen Receptor Modulators);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);免疫沉淀法(Immunoprecipitation);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 裸(Mice, Nude);中年人(Middle Aged);磷酰化(Phosphorylation);受体, 雌激素(Receptors, Estrogen);他莫昔芬(Tamoxifen);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays);Y盒结合蛋白质1(Y-Box-Binding Protein 1)

DOI 10.1158/0008-5472.CAN-16-1593

PMID 27879270

发布时间 2018-12-02

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Breast Cancer Resistance to Antiestrogens Is Enhanced by Increased ER Degradation and ERBB2 Expression.

Cancer research

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Breast Cancer Resistance to Antiestrogens Is Enhanced by Increased ER Degradation and ERBB2 Expression.

Cancer research

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Cancer research

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