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首页> Journal of nuclear medicine : official publication, Society of Nuclear Medicine> Novel "Add-On" Molecule Based on Evans Blue Confers Superior Pharmacokinetics and Transforms Drugs to Theranostic Agents.

Novel "Add-On" Molecule Based on Evans Blue Confers Superior Pharmacokinetics and Transforms Drugs to Theranostic Agents.

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作者： Haojun,Chen ^[1] ; Orit,Jacobson ^[2] ; Gang,Niu ^[2] ; Ido D,Weiss ^[2] ; Dale O,Kiesewetter ^[3] ; Yi,Liu ^[2] ; Ying,Ma ^[2] ; Hua,Wu ^[2] ; Xiaoyuan,Chen ^[1]

作者单位： Department of Nuclear Medicine, Xiamen Cancer Hospital of the First Affiliated Hospital of Xiamen University, Xiamen, China. ^[1] Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland; and. ^[2] Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland. ^[3] Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland; and shawn.chen@nih.gov. ^[4]

关键词 90Y Evans blue RGD peptide albumin binding integrin theranostics

主题词动物(Animals);细胞系, 肿瘤(Cell Line, Tumor);铜放射性同位素(Copper Radioisotopes);伊文思蓝(Evans Blue);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);杂环化合物(Heterocyclic Compounds);杂环化合物, 1环(Heterocyclic Compounds, 1-Ring);人类(Humans);整合素αVβ3(Integrin alphaVbeta3);小鼠(Mice);寡肽类(Oligopeptides);正电子发射断层显像术(Positron-Emission Tomography);放射化学(Radiochemistry);放射性药物(Radiopharmaceuticals);组织分布(Tissue Distribution);钇放射性同位素(Yttrium Radioisotopes)

DOI 10.2967/jnumed.116.182097

PMID 27879373

发布时间 2018-11-13

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准确一般字义偏差语意偏离译文作用小提交

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Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Journal of nuclear medicine

2017年58卷4期

590-597页

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