Sample injection strategy to increase throughput in counter-current chromatography: Case study of Honokiol purification.

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作者： Aihua,Peng ^[1] ; Peter,Hewitson ^[2] ; Haoyu,Ye ^[1] ; Liansuo,Zu ^[3] ; Ian,Garrard ^[2] ; Ian,Sutherland ^[2] ; Lijuan,Chen ^[4] ; Svetlana,Ignatova ^[5]

作者单位： State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Centre for Bio Therapy, Chengdu 610041, China. ^[1] Advanced Bioprocessing Centre, College of Engineering, Design and Physical Sciences, Brunel University London, Uxbridge, UB8 3PH, UK. ^[2] Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University and Collaborative Innovation Centre for Biotherapy, Beijing 100084, China. ^[3] State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Centre for Bio Therapy, Chengdu 610041, China. Electronic address: chenlijuan125@163.com. ^[4] Advanced Bioprocessing Centre, College of Engineering, Design and Physical Sciences, Brunel University London, Uxbridge, UB8 3PH, UK. Electronic address: svetlana.ignatova@brunel.ac.uk. ^[5]

关键词 CCC Counter-current chromatography Honokiol Magnolol Sample injection Sample loading Throughput

主题词抗肿瘤药, 植物(Antineoplastic Agents, Phytogenic);联苯化合物(Biphenyl Compounds);反流分布法(Countercurrent Distribution);木酚素类(Lignans);木兰属(Magnolia);植物提取物(Plant Extracts);溶剂(Solvents)

DOI 10.1016/j.chroma.2016.10.040

PMID 27884427

发布时间 2018-12-02

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