Loss of Cbl-PI3K interaction modulates the periosteal response to fracture by enhancing osteogenic commitment and differentiation.-论文-万方医学网

第一作者： Vanessa,Scanlon

第一单位： Department of Orthopaedic Surgery, United States.

作者： Vanessa,Scanlon ^[1] ; Bhavita,Walia ^[2] ; Jungeun,Yu ^[1] ; Marc,Hansen ^[3] ; Hicham,Drissi ^[2] ; Peter,Maye ^[4] ; Archana,Sanjay ^[5]

作者单位： Department of Orthopaedic Surgery, United States. ^[1] Department of Orthopaedic Surgery, United States; Department of Genetics and Genome Sciences, United States. ^[2] Department of Genetics and Genome Sciences, United States; Center for Molecular Medicine, United States. ^[3] Department of Reconstructive Sciences, UConn Health, Farmington, CT, United States. ^[4] Department of Orthopaedic Surgery, United States; Department of Genetics and Genome Sciences, United States. Electronic address: asanjay@uchc.edu. ^[5]

主题词碱性磷酸酶(Alkaline Phosphatase);动物(Animals);细胞计数(Cell Count);细胞分化(Cell Differentiation);细胞谱系(Cell Lineage);细胞核(Cell Nucleus);细胞增殖(Cell Proliferation);骨折愈合(Fracture Healing);骨折(Fractures, Bone);中胚层(Mesoderm);小鼠, 近交C57BL(Mice, Inbred C57BL);突变(Mutation);骨生成(Osteogenesis);骨膜(Periosteum);磷酸肌醇3-激酶(Phosphatidylinositol 3-Kinase);磷酰化(Phosphorylation);蛋白质结合(Protein Binding);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);原癌基因蛋白质c-cbl(Proto-Oncogene Proteins c-cbl);增量调节(Up-Regulation)

DOI 10.1016/j.bone.2016.11.020

PMID 27884787

发布时间 2018-11-13

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Loss of Cbl-PI3K interaction modulates the periosteal response to fracture by enhancing osteogenic commitment and differentiation.

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Loss of Cbl-PI3K interaction modulates the periosteal response to fracture by enhancing osteogenic commitment and differentiation.

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