Stability behaviour of antiretroviral drugs and their combinations. 5: Characterization of novel degradation products of abacavir sulfate by mass and nuclear magnetic resonance spectrometry.

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作者： Moolchand,Kurmi ^[1] ; Archana,Sahu ^[1] ; Saranjit,Singh ^[2]

作者单位： Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S. Nagar 160 062 Punjab, India. ^[1] Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S. Nagar 160 062 Punjab, India. Electronic address: ssingh@niper.ac.in. ^[2]

关键词 Abacavir sulfate Degradation products Mass spectrometry NMR spectrometry Stress testing

主题词抗逆转录病毒药(Anti-Retroviral Agents);色谱法, 高压液相(Chromatography, High Pressure Liquid);双脱氧核苷类(Dideoxynucleosides);复方合剂(Drug Combinations);药物稳定性(Drug Stability);磁共振波谱学(Magnetic Resonance Spectroscopy);质谱分析法(Mass Spectrometry)

DOI 10.1016/j.jpba.2016.10.019

PMID 27889293

发布时间 2017-12-08

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