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Structure of the germline genome of <i>Tetrahymena thermophila</i> and relationship to the massively rearranged somatic genome.

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第一作者： Eileen P,Hamilton

第一单位： Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, Santa Barbara, United States.

作者： Eileen P,Hamilton ^[1] ; Aurélie,Kapusta ^[2] ; Piroska E,Huvos ^[3] ; Shelby L,Bidwell ^[4] ; Nikhat,Zafar ^[4] ; Haibao,Tang ^[4] ; Michalis,Hadjithomas ^[4] ; Vivek,Krishnakumar ^[4] ; Jonathan H,Badger ^[4] ; Elisabet V,Caler ^[4] ; Carsten,Russ ^[5] ; Qiandong,Zeng ^[5] ; Lin,Fan ^[5] ; Joshua Z,Levin ^[5] ; Terrance,Shea ^[5] ; Sarah K,Young ^[5] ; Ryan,Hegarty ^[5] ; Riza,Daza ^[5] ; Sharvari,Gujja ^[5] ; Jennifer R,Wortman ^[5] ; Bruce W,Birren ^[5] ; Chad,Nusbaum ^[5] ; Jainy,Thomas ^[2] ; Clayton M,Carey ^[2] ; Ellen J,Pritham ^[2] ; Cédric,Feschotte ^[2] ; Tomoko,Noto ^[6] ; Kazufumi,Mochizuki ^[6] ; Romeo,Papazyan ^[7] ; Sean D,Taverna ^[7] ; Paul H,Dear ^[8] ; Donna M,Cassidy-Hanley ^[9] ; Jie,Xiong ^[10] ; Wei,Miao ^[10] ; Eduardo,Orias ^[1] ; Robert S,Coyne ^[4]

作者单位： Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, Santa Barbara, United States. ^[1] Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, United States. ^[2] Biochemistry and Molecular Biology, Southern Illinois University, Carbondale, United States. ^[3] J. Craig Venter Institute, Rockville, United States. ^[4] Eli and Edythe L. Broad Institute of Harvard and MIT, Cambridge, United States. ^[5] Institute of Molecular Biotechnology, Vienna, Austria. ^[6] Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, United States. ^[7] MRC Laboratory of Molecular Biology, Cambridge, United Kingdom. ^[8] Department of Microbiology and Immunology, Cornell University, Ithaca, United States. ^[9] Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China. ^[10]

关键词 Tetrahymena thermophila centromere chromosome breakage chromosomes evolutionary biology genes genome rearrangement genomics intermal eliminated sequence transposable element

医学主题词基因重排(Gene Rearrangement);基因组, 原虫(Genome, Protozoan);序列分析, DNA(Sequence Analysis, DNA);嗜热四膜虫(Tetrahymena thermophila)

DOI 10.7554/eLife.19090

PMID 27892853

发布时间 2025-05-30

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