Targeting the endocannabinoid/CB1 receptor system for treating obesity in Prader-Willi syndrome.-论文-万方医学网

第一作者： Ibrahim,Knani

第一单位： Obesity and Metabolism Laboratory, The Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.

作者： Ibrahim,Knani ^[1] ; Brian J,Earley ^[2] ; Shiran,Udi ^[1] ; Alina,Nemirovski ^[1] ; Rivka,Hadar ^[1] ; Asaad,Gammal ^[1] ; Resat,Cinar ^[2] ; Harry J,Hirsch ^[3] ; Yehuda,Pollak ^[3] ; Itai,Gross ^[3] ; Talia,Eldar-Geva ^[4] ; Daniela P,Reyes-Capo ^[5] ; Joan C,Han ^[6] ; Andrea M,Haqq ^[7] ; Varda,Gross-Tsur ^[3] ; Rachel,Wevrick ^[8] ; Joseph,Tam ^[9]

作者单位： Obesity and Metabolism Laboratory, The Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel. ^[1] Laboratory of Physiologic Studies, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA. ^[2] Neuropediatric Unit, Department of Pediatrics, Shaare Zedek Medical Center, Jerusalem, Israel. ^[3] Reproductive Endocrinology and Genetics Unit, Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Jerusalem, Israel. ^[4] Unit on Metabolism and Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA. ^[5] Unit on Metabolism and Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA; Department of Pediatrics, University of Tennessee Health Science Center, Children's Foundation Research Institute, Le Bonheur Children's Hospital, Memphis, TN, USA; Department of Physiology, University of Tennessee Health Science Center, Memphis, TN, USA. ^[6] Department of Pediatrics, University of Alberta, Edmonton, AB, Canada. ^[7] Department of Medical Genetics, University of Alberta, Edmonton, AB Canada. ^[8] Obesity and Metabolism Laboratory, The Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel. Electronic address: yossit@ekmd.huji.ac.il. ^[9]

主题词成年人(Adult);动物(Animals);抗原, 肿瘤(Antigens, Neoplasm);花生四烯酸类(Arachidonic Acids);体重(Body Weight);病例对照研究(Case-Control Studies);疾病模型, 动物(Disease Models, Animal);内源性大麻酚类(Endocannabinoids);女(雌)性(Female);甘油酯类(Glycerides);人类(Humans);下丘脑(Hypothalamus);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);Prader-Willi综合征(Prader-Willi Syndrome);蛋白质类(Proteins);吡唑类(Pyrazoles);受体, 大麻酚, CB1(Receptor, Cannabinoid, CB1);磺胺类(Sulfonamides);体重减轻(Weight Loss)

DOI 10.1016/j.molmet.2016.10.004

PMID 27900261

发布时间 2019-01-15

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Targeting the endocannabinoid/CB1 receptor system for treating obesity in Prader-Willi syndrome.

Molecular metabolism

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Molecular metabolism

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Targeting the endocannabinoid/CB1 receptor system for treating obesity in Prader-Willi syndrome.

Molecular metabolism

相似文献

Molecular metabolism

相关期刊

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