换一批
换一批<i>SOS2</i> and <i>ACP1</i> Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function.
作者：
Man,Li [1]
;
Yong,Li [2]
;
Olivia,Weeks [3]
;
Vladan,Mijatovic [4]
;
Alexander,Teumer [5]
;
Jennifer E,Huffman [6]
;
Gerard,Tromp [7]
;
Christian,Fuchsberger [8]
;
Mathias,Gorski [9]
;
Leo-Pekka,Lyytikäinen [10]
;
Teresa,Nutile [11]
;
Sanaz,Sedaghat [12]
;
Rossella,Sorice [13]
;
Adrienne,Tin [14]
;
Qiong,Yang [15]
;
Tarunveer S,Ahluwalia [16]
;
Dan E,Arking [17]
;
Nathan A,Bihlmeyer [16]
;
Carsten A,Böger [1]
;
Robert J,Carroll [18]
;
Daniel I,Chasman [19]
;
Marilyn C,Cornelis [20]
;
Abbas,Dehghan [21]
;
Jessica D,Faul [21]
;
Mary F,Feitosa [14]
;
Giovanni,Gambaro [22]
;
Paolo,Gasparini [4]
;
Franco,Giulianini [22]
;
Iris,Heid [23]
;
Jinyan,Huang [24]
;
Medea,Imboden [17]
;
Anne U,Jackson [25]
;
Janina,Jeff [26]
;
Min A,Jhun [27]
;
Ronit,Katz [28]
;
Annette,Kifley [29]
;
Tuomas O,Kilpeläinen [13]
;
Ashish,Kumar [30]
;
Markku,Laakso [31]
;
Ruifang,Li-Gao [32]
;
Kurt,Lohman [33]
;
Yingchang,Lu [12]
;
Reedik,Mägi [34]
;
Giovanni,Malerba [35]
;
Evelin,Mihailov [36]
;
Karen L,Mohlke [37]
;
Dennis O,Mook-Kanamori [19]
;
Antonietta,Robino [33]
;
Douglas,Ruderfer [38]
;
Erika,Salvi [17]
;
Ursula M,Schick [39]
;
Christina-Alexandra,Schulz [34]
;
Albert V,Smith [40]
;
Jennifer A,Smith [41]
;
Michela,Traglia [40]
;
Laura M,Yerges-Armstrong [42]
;
Wei,Zhao [43]
;
Mark O,Goodarzi [44]
;
Aldi T,Kraja [45]
;
Chunyu,Liu [46]
;
Jennifer,Wessel [47]
;
CHARGE Glycemic-T2D Working Group, [48]
;
CHARGE Blood Pressure Working Group, [49]
;
Eric,Boerwinkle [50]
;
Ingrid B,Borecki [51]
;
Jette,Bork-Jensen [35]
;
Erwin P,Bottinger [52]
;
Daniele,Braga [53]
;
Ivan,Brandslund [35]
;
Jennifer A,Brody [54]
;
Archie,Campbell [55]
;
David J,Carey [56]
;
Cramer,Christensen [7]
;
Josef,Coresh [57]
;
Errol,Crook [58]
;
Gary C,Curhan [59]
;
Daniele,Cusi [26]
;
Ian H,de Boer [19]
;
Aiko P J,de Vries [34]
;
Joshua C,Denny [47]
;
Olivier,Devuyst [60]
;
Albert W,Dreisbach [61]
;
Karlhans,Endlich [8]
;
Tõnu,Esko [9]
;
Oscar H,Franco [62]
;
Tibor,Fulop [1]
;
Glenn S,Gerhard [63]
;
Charlotte,Glümer [64]
;
Omri,Gottesman [47]
;
Niels,Grarup [65]
;
Vilmundur,Gudnason [36]
;
Torben,Hansen [66]
;
Tamara B,Harris [22]
;
Caroline,Hayward [67]
;
Lynne,Hocking [68]
;
Albert,Hofman [69]
;
Frank B,Hu [21]
;
Lise Lotte N,Husemoen [40]
;
Rebecca D,Jackson [70]
;
Torben,Jørgensen [71]
;
Marit E,Jørgensen [17]
;
Mika,Kähönen [68]
;
Sharon L R,Kardia [72]
;
Wolfgang,König [73]
;
Charles,Kooperberg [34]
;
Jennifer,Kriebel [19]
;
Lenore J,Launer [50]
;
Torsten,Lauritzen [19]
;
Terho,Lehtimäki [74]
;
Daniel,Levy [75]
;
Pamela,Linksted [8]
;
Allan,Linneberg [76]
;
Yongmei,Liu [77]
;
Ruth J F,Loos [17]
;
Antonio,Lupo [78]
;
Christine,Meisinger [73]
;
Olle,Melander [79]
;
Andres,Metspalu [73]
;
Paul,Mitchell [20]
;
Matthias,Nauck [14]
;
Peter,Nürnberg [35]
;
Marju,Orho-Melander [80]
;
Afshin,Parsa [81]
;
Oluf,Pedersen [82]
;
Annette,Peters [48]
;
Ulrike,Peters [83]
;
Ozren,Polasek [83]
;
David,Porteous [75]
;
Nicole M,Probst-Hensch [84]
;
Bruce M,Psaty [15]
;
Lu,Qi [7]
;
Olli T,Raitakari [8]
;
Alex P,Reiner [73]
;
Rainer,Rettig [85]
;
Paul M,Ridker [74]
;
Fernando,Rivadeneira [86]
;
Jacques E,Rossouw [34]
;
Frank,Schmidt [87]
;
David,Siscovick [83]
;
Nicole,Soranzo [49]
;
Konstantin,Strauch [40]
;
Daniela,Toniolo [37]
;
Stephen T,Turner [88]
;
André G,Uitterlinden [89]
;
Sheila,Ulivi [90]
;
Dinesh,Velayutham [49]
;
Uwe,Völker [91]
;
Henry,Völzke [19]
;
Melanie,Waldenberger [83]
;
Jie Jin,Wang [83]
;
David R,Weir [92]
;
Daniel,Witte [48]
;
Helena,Kuivaniemi [93]
;
Caroline S,Fox [8]
;
Nora,Franceschini [33]
;
Wolfram,Goessling [61]
;
Anna,Köttgen [94]
;
Audrey Y,Chu [95]
作者单位：
Department of Epidemiology, Johns Hopkins University, Baltimore, Maryland.
[1]
Division of Nephrology and Department of Human Genetics, University of Utah, Salt Lake City, Utah.
[2]
Division of Genetic Epidemiology, Medical Center - University of Freiburg, Freiburg, Germany.
[3]
Genetics Division.
[4]
Department of Life and Reproduction Sciences, and.
[5]
Institute for Community Medicine.
[6]
National Heart, Lung, and Blood Institute's Framingham Heart Study and the Center for Population Studies, Framingham, Massachusetts.
[7]
Center for Genomic & Experimental Medicine, Institute of Genetics and Molecular Medicine.
[8]
The Sigfried and Janet Weis Center for Research, Geisinger Health System, Danville, Pennsylvania.
[9]
Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa.
[10]
Center for Biomedicine, European Academy of Bolzano/Bozen, affiliated to the University of Lübeck, Bolzano/Bozen, Italy.
[11]
Department of Biostatistics, Center for Statistical Genetics.
[12]
Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany.
[13]
Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.
[14]
Department of Clinical Chemistry, Fimlab Laboratories and University of Tampere School of Medicine, Tampere, Finland.
[15]
Institute of Genetics and Biophysics "Adriano Buzzati-Traverso", Napoli, Italy.
[16]
Department of Epidemiology, and.
[17]
Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.
[18]
Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, and.
[19]
Steno Diabetes Center, Gentofte, Denmark.
[20]
McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
[21]
Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee.
[22]
Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts.
[23]
Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
[24]
Survey Research Center, Institute for Social Research, and.
[25]
Department of Genetics, School of Medicine, Washington University School of Medicine, St. Louis, Missouri.
[26]
Division of Nephrology, Gemelli Foundation University Hospital, Catholic University, Rome, Italy.
[27]
Institute for Maternal and Child Health, IRCCS "Burlo Garofolo", University of Trieste, Trieste, Italy.
[28]
Division of Preventive Medicine.
[29]
Institute of Genetic Epidemiology and.
[30]
Institute of Hematology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
[31]
State Key Laboratory of Medical Genomics, Shanghai, China.
[32]
Swiss Tropical and Public Health Institute, Basel, Switzerland.
[33]
The Charles Bronfman Institute for Personalized Medicine, and.
[34]
Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan.
[35]
Kidney Research Institute.
[36]
Center for Vision Research, Department of Ophthalmology and Westmead Millennium Institute for Medical Research, University of Sydney, Westmead, Sydney, New South Wales, Australia.
[37]
Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
[38]
Division of Public Health Sciences, Biostatistical Sciences, and.
[39]
Estonian Genome Center of University of Tartu, Tartu, Estonia.
[40]
Section of Biology and Genetics, Department of Life and Reproduction Sciences, University of Verona, Verona, Italy.
[41]
Department of Genetics, and.
[42]
Department of Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
[43]
Epidemiology Section, Department of Biostatistics Epidemiology & Scientific Computing, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
[44]
Institute for Maternal and Child Health - IRCCS "Burlo Garofolo", Trieste, Italy.
[45]
Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York.
[46]
Department of Health Science, University of Milano, Milano, Italy.
[47]
Fred Hutchinson Cancer Research Center, Seattle, Washington.
[48]
Department of Clinical Science, Lund University, Malmö, Sweden.
[49]
Icelandic Heart Association, Kopavogur, Iceland.
[50]
Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
[51]
San Raffaele Scientific Institute, Milano, Italy.
[52]
Program in Personalized and Genomic Medicine and Department of Medicine, School of Medicine, University of Maryland, Baltimore, Maryland.
[53]
Department of Medicine and Department of Biomedical Sciences, and.
[54]
Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, California.
[55]
Division of Statistical Genomics, Department of Genetics and Center for Genome Sciences and Systems Biology, Washington University, St. Louis, Missouri.
[56]
Department of Epidemiology, Fairbanks School of Public Health, Indianapolis, Indiana.
[57]
Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana.
[58]
The Human Genetics Center and Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas.
[59]
Department of Clinical Biochemistry, and.
[60]
Cardiovascular Health Research Unit, Department of Medicine, and.
[61]
Department of Internal Medicine and Endocrinology, Vejle Hospital, Vejle, Denmark.
[62]
Department of Medicine, University of South Alabama College of Medicine, Mobile, Alabama.
[63]
Renal Division and Channing Laboratory, Brigham and Women's Hospital, Boston, Massachusetts.
[64]
Division of Nephrology, San Paolo Hospital, Milan, Italy.
[65]
Division of Nephrology, Department of Medicine, Leiden University Medical Center and Leiden University, The Netherlands.
[66]
University of Zurich, Institute of Physiology, Zurich Center for Integrative Human Physiology, Mechanisms of Inherited Kidney Disorders Group, Zürich, Switzerland.
[67]
Department of Medicine, University of Mississippi, Jackson, Mississippi.
[68]
Department of Anatomy and Cell Biology.
[69]
Division of Endocrinology, Children's Hospital Boston, Boston, Massachusetts.
[70]
Department of Genetics, Harvard Medical School, Boston, Massachusetts.
[71]
Department of Medical Genetics and Molecular Biochemistry, Temple University School of Medicine, Philadelphia, Pennsylvania.
[72]
Research Center for Prevention and Health, The Capital Region of Denmark, Glostrup University Hospital, Glostrup, Denmark.
[73]
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
[74]
National Institutes on Aging, Bethesda, Maryland.
[75]
Medical Research Council Human Genetics, Institute of Genetics and Molecular Medicine, and.
[76]
Division of Applied Health Sciences, University of Aberdeen, Aberdeen, Scotland, United Kindom.
[77]
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts.
[78]
Department of Internal Medicine, The Ohio State University, Columbia, Ohio.
[79]
Department of Internal Medicine II, Cardiology, University of Ulm Medical Center, Ulm, Germany.
[80]
The German Heart Center Munich, Technical University of Munich, Munich, Germany.
[81]
German Center for Cardiovascular Research, partner site Munich Heart Alliance, Munich, Germany.
[82]
Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.
[83]
Department of General Practice, Aarhus University, Aarhus, Denmark.
[84]
Department of Clinical Experimental Research, Rigshospitalet, Denmark.
[85]
Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
[86]
Renal Unit, Department of Medicine, University Hospital of Verona, Verona, Italy.
[87]
Institute of Clinical Chemistry and Laboratory Medicine.
[88]
German Center for Cardiovascular Research, partner site Greifswald, Greifswald, Germany.
[89]
Cologne Center for Genomics, University of Cologne, Cologne, Germany.
[90]
Division of Nephrology, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland.
[91]
German Center for Cardiovascular Disease Research, Munich, Germany.
[92]
Center for Population Health Sciences, University of Edinburgh, Edinburgh, Scotland, United Kingdom.
[93]
Departments of Epidemiology and Health Services, University of Washington, Seattle, Washington.
[94]
Group Health Research Institute, Group Health Cooperative, Seattle, Washington.
[95]
Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, and Research Center of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.
[96]
Institute of Physiology, and.
[97]
Cardiovascular Medicine Division, and.
[98]
Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
[99]
National Heart, Lung, and Blood Institute, Bethesda, Maryland.
[100]
Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
[101]
Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany.
[102]
Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota.
[103]
German Center for Diabetes Research, partner site Greifswald, Greifswald, Germany.
[104]
Department of Public Health, Aarhus University, Aarhus, Denmark.
[105]
Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina.
[106]
Harvard Stem Cell Institute, Cambridge, Massachusetts; and.
[107]
Gastroenterology Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
[108]
Dana-Farber Cancer Institute, Boston, Massachusetts.
[109]
Department of Epidemiology, Johns Hopkins University, Baltimore, Maryland; audrey.chu@nih.gov anna.koettgen@uniklinik-freiburg.de.
[110]
National Heart, Lung, and Blood Institute's Framingham Heart Study and the Center for Population Studies, Framingham, Massachusetts; audrey.chu@nih.gov anna.koettgen@uniklinik-freiburg.de.
[111]
主题词
动物(Animals);基因座(Genetic Loci);全基因组关联研究(Genome-Wide Association Study);肾小球滤过率(Glomerular Filtration Rate);人类(Humans);肾(Kidney);蛋白质酪氨酸磷酸酶类(Protein Tyrosine Phosphatases);原癌基因蛋白质类(Proto-Oncogene Proteins);SOS蛋白质类(Son of Sevenless Proteins);斑马鱼(Zebrafish)
DOI
10.1681/ASN.2016020131
PMID
27920155
发布时间
2023-04-11
- 浏览5
Journal of the American Society of Nephrology
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