TPPU protects tau from H<sub>2</sub>O<sub>2</sub>-induced hyperphosphorylation in HEK293/tau cells by regulating PI3K/AKT/GSK-3β pathway.

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作者： En-Sheng,Yao ^[1] ; Yan,Tang ^[2] ; Xing-Hua,Liu ^[3] ; Ming-Huan,Wang ^[4]

作者单位： Department of Neurology, Tongji Hospital, Tongji Medicine College, Huazhong University of Science and Technology, Wuhan, 430030, China. ^[1] Department of Neurology, Shihezi University, Shihezi, 832008, China. ^[2] Department of Geriatrics, The First Affiliated Hospital, School of Medicine, Shihezi University, Shihezi, 832008, China. ^[3] Department of Neurology, Tongji Hospital, Tongji Medicine College, Huazhong University of Science and Technology, Wuhan, 430030, China. liu_xingh@126.com. ^[4]

关键词 Alzheimer’s disease GSK-3β TPPU tau

主题词细胞存活(Cell Survival);酶抑制剂(Enzyme Inhibitors);HEK293细胞(HEK293 Cells);人类(Humans);过氧化氢(Hydrogen Peroxide);氧化性应激(Oxidative Stress);苯脲化合物(Phenylurea Compounds);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);磷酰化(Phosphorylation);哌啶类(Piperidines);蛋白质加工, 转译后(Protein Processing, Post-Translational);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);信号传导(Signal Transduction);tau蛋白质类(tau Proteins)

DOI 10.1007/s11596-016-1662-z

PMID 27924507

发布时间 2018-11-13

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Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban

2016年36卷6期

785-790页

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TPPU protects tau from H<sub>2</sub>O<sub>2</sub>-induced hyperphosphorylation in HEK293/tau cells by regulating PI3K/AKT/GSK-3β pathway.

Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban

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Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban

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TPPU protects tau from H<sub>2</sub>O<sub>2</sub>-induced hyperphosphorylation in HEK293/tau cells by regulating PI3K/AKT/GSK-3β pathway.

Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban

相似文献

Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban

相关期刊

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