Inhibiting PI3K-AKt signaling pathway is involved in antitumor effects of ginsenoside Rg3 in lung cancer cell.

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作者： Qipeng,Xie ^[1] ; Huaikai,Wen ^[1] ; Qiong,Zhang ^[2] ; Weihe,Zhou ^[3] ; Xiaoming,Lin ^[4] ; Deyao,Xie ^[4] ; Yu,Liu ^[5]

作者单位： Department of Laboratory Medicine, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China. ^[1] Department of Gynaecology and Obstetrics, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China. ^[2] Department of Cardiothoracic Surgery, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China. ^[3] Department of Cardiothoracic Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China. ^[4] Department of Cardiothoracic Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China. Electronic address: 48936053@qq.com. ^[5]

关键词 Apoptosis Ginsenoside Rg3 Lung cancer PI3K/Akt

主题词腺癌(Adenocarcinoma);动物(Animals);抗肿瘤药, 植物(Antineoplastic Agents, Phytogenic);细胞系, 肿瘤(Cell Line, Tumor);剂量效应关系, 药物(Dose-Response Relationship, Drug);基因表达调控(Gene Expression Regulation);人参皂甙类(Ginsenosides);人类(Humans);肺肿瘤(Lung Neoplasms);小鼠(Mice);小鼠, 裸(Mice, Nude);肿瘤, 实验性(Neoplasms, Experimental);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);植物药疗法(Phytotherapy);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);信号传导(Signal Transduction)

DOI 10.1016/j.biopha.2016.11.096

PMID 27930981

发布时间 2017-02-22

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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

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Inhibiting PI3K-AKt signaling pathway is involved in antitumor effects of ginsenoside Rg3 in lung cancer cell.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

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Inhibiting PI3K-AKt signaling pathway is involved in antitumor effects of ginsenoside Rg3 in lung cancer cell.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

相关期刊

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