TNAP stimulates vascular smooth muscle cell trans-differentiation into chondrocytes through calcium deposition and BMP-2 activation: Possible implication in atherosclerotic plaque stability.

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第一作者： Maya,Fakhry

第一单位： Univ Lyon, University Lyon 1, ICBMS, UMR CNRS 5246, F-69622 Lyon, France; Lebanese University, Laboratory of Cancer Biology and Molecular Immunology, EDST-PRASE, Hadath-Beirut, Lebanon.

作者： Maya,Fakhry ^[1] ; Monika,Roszkowska ^[2] ; Anne,Briolay ^[3] ; Carole,Bougault ^[3] ; Alain,Guignandon ^[4] ; Juan Ignacio,Diaz-Hernandez ^[5] ; Miguel,Diaz-Hernandez ^[5] ; Slawomir,Pikula ^[6] ; René,Buchet ^[3] ; Eva,Hamade ^[7] ; Bassam,Badran ^[7] ; Laurence,Bessueille ^[3] ; David,Magne ^[8]

作者单位： Univ Lyon, University Lyon 1, ICBMS, UMR CNRS 5246, F-69622 Lyon, France; Lebanese University, Laboratory of Cancer Biology and Molecular Immunology, EDST-PRASE, Hadath-Beirut, Lebanon. ^[1] Univ Lyon, University Lyon 1, ICBMS, UMR CNRS 5246, F-69622 Lyon, France; Laboratory of Biochemistry of Lipids, Department of Biochemistry, Nencki Institute of Experimental Biology of Polish Academy of Sciences, Warsaw, Poland. ^[2] Univ Lyon, University Lyon 1, ICBMS, UMR CNRS 5246, F-69622 Lyon, France. ^[3] Univ Lyon, Université Jean Monnet Saint-Etienne, LBTO, UMR INSERM 1059, F-42023 Saint-Etienne, France. ^[4] Universidad Complutense de Madrid, Facultad de Veterinaria, Dpt. Bioquimica y Biologia Molecular IV, Madrid, Spain. ^[5] Laboratory of Biochemistry of Lipids, Department of Biochemistry, Nencki Institute of Experimental Biology of Polish Academy of Sciences, Warsaw, Poland. ^[6] Lebanese University, Laboratory of Cancer Biology and Molecular Immunology, EDST-PRASE, Hadath-Beirut, Lebanon. ^[7] Univ Lyon, University Lyon 1, ICBMS, UMR CNRS 5246, F-69622 Lyon, France. Electronic address: david.magne@univ-lyon1.fr. ^[8]

关键词 Chondrocytes Inorganic pyrophosphate Microcalcification Tissue-nonspecific alkaline phosphatase VSMCs Vascular calcification

主题词碱性磷酸酶(Alkaline Phosphatase);动物(Animals);骨形态发生蛋白质2(Bone Morphogenetic Protein 2);钙化, 生理性(Calcification, Physiologic);钙(Calcium);细胞系(Cell Line);细胞转分化(Cell Transdifferentiation);软骨细胞(Chondrocytes);软骨发生(Chondrogenesis);小鼠(Mice);肌, 平滑, 血管(Muscle, Smooth, Vascular);斑块, 动脉粥样硬化(Plaque, Atherosclerotic)

DOI 10.1016/j.bbadis.2016.12.003

PMID 27932058

发布时间 2022-02-02

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Biochimica et biophysica acta. Molecular basis of disease

2017年1863卷3期

643-653页

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TNAP stimulates vascular smooth muscle cell trans-differentiation into chondrocytes through calcium deposition and BMP-2 activation: Possible implication in atherosclerotic plaque stability.

Biochimica et biophysica acta. Molecular basis of disease

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Biochimica et biophysica acta. Molecular basis of disease

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TNAP stimulates vascular smooth muscle cell trans-differentiation into chondrocytes through calcium deposition and BMP-2 activation: Possible implication in atherosclerotic plaque stability.

Biochimica et biophysica acta. Molecular basis of disease

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Biochimica et biophysica acta. Molecular basis of disease

相关期刊

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