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Immunogenicity of self tumor associated proteins is enhanced through protein truncation.

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第一作者： Tim,Kottke

第一单位： Department of Molecular Medicine, Mayo Clinic , Rochester, Minnesota, USA.

作者： Tim,Kottke ^[1] ; Kevin G,Shim ^[2] ; Vanesa,Alonso-Camino ^[1] ; Shane,Zaidi ^[1] ; Rosa,Maria Diaz ^[1] ; Jose,Pulido ^[3] ; Jill,Thompson ^[1] ; Karishma R,Rajani ^[1] ; Laura,Evgin ^[1] ; Elizabeth,Ilett ^[4] ; Hardev,Pandha ^[5] ; Kevin,Harrington ^[6] ; Peter,Selby ^[4] ; Alan,Melcher ^[6] ; Richard,Vile ^[7]

作者单位： Department of Molecular Medicine, Mayo Clinic , Rochester, Minnesota, USA. ^[1] Department of Molecular Medicine, Mayo Clinic, Rochester, Minnesota, USA; Department of Immunology, Mayo Clinic, Rochester, Minnesota, USA. ^[2] Department of Molecular Medicine, Mayo Clinic, Rochester, Minnesota, USA; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, USA. ^[3] Cancer Research UK Clinical Center, St. James' University Hospital , Leeds, UK. ^[4] University of Surrey, Guildford , UK. ^[5] The Institute of Cancer Research , London, UK. ^[6] Department of Molecular Medicine, Mayo Clinic, Rochester, Minnesota, USA; Department of Immunology, Mayo Clinic, Rochester, Minnesota, USA; Cancer Research UK Clinical Center, St. James' University Hospital, Leeds, UK. ^[7]

DOI 10.1038/mto.2016.30

PMID 27933315

发布时间 2025-05-30

基金项目

21855/CRUK_/Cancer Research UK/United Kingdom P50 CA108961/CA/NCI NIH HHS/United States R01 CA175386/CA/NCI NIH HHS/United States RP-PG-0707-10101/DH_/Department of Health/United Kingdom T32 GM065841/GM/NIGMS NIH HHS/United States 13244/CRUK_/Cancer Research UK/United Kingdom

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Molecular therapy oncolytics

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