Small-molecule inhibition of STOML3 oligomerization reverses pathological mechanical hypersensitivity.

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作者： Christiane,Wetzel ^[1] ; Simone,Pifferi ^[1] ; Cristina,Picci ^[1] ; Caglar,Gök ^[2] ; Diana,Hoffmann ^[1] ; Kiran K,Bali ^[1] ; André,Lampe ^[3] ; Liudmila,Lapatsina ^[4] ; Raluca,Fleischer ^[5] ; Ewan St John,Smith ^[1] ; Valérie,Bégay ^[1] ; Mirko,Moroni ^[1] ; Luc,Estebanez ^[6] ; Johannes,Kühnemund ^[1] ; Jan,Walcher ^[1] ; Edgar,Specker ^[1] ; Martin,Neuenschwander ^[3] ; Jens Peter,von Kries ^[1] ; Volker,Haucke ^[1] ; Rohini,Kuner ^[5] ; James F A,Poulet ^[5] ; Jan,Schmoranzer ^[5] ; Kate,Poole ^[5] ; Gary R,Lewin ^[4]

作者单位： Department of Neuroscience, Max Delbrück Center for Molecular Medicine, Berlin, Germany. ^[1] Department of Biomedical Sciences, Section of Cytomorphology, University of Cagliari, Monserrato (California), Italy. ^[2] Neuroscience Research Center and Cluster of Excellence NeuroCure, Charité-Universitätsmedizin, Berlin, Germany. ^[3] Institute of Pharmacology, Heidelberg University, Heidelberg, Germany. ^[4] Leibniz-Institut für Molekulare Pharmakologie (FMP), Berlin, Germany. ^[5] Department of Pharmacology, University of Cambridge, Cambridge, UK. ^[6] Freie Universität Berlin, Berlin, Germany. ^[7] Department of Physiology and EMBL Australia Node for Single Molecule Science, School of Medical Sciences, UNSW, Sydney, Australia. ^[8]