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Combination of metformin and sorafenib suppresses proliferation and induces autophagy of hepatocellular carcinoma via targeting the mTOR pathway.

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第一作者： Sunbin,Ling

第一单位： Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, P.R. China.

作者： Sunbin,Ling ^[1] ; Lei,Song ^[2] ; Ning,Fan ^[3] ; Tingting,Feng ^[4] ; Lu,Liu ^[5] ; Xu,Yang ^[5] ; Mingjie,Wang ^[5] ; Yanling,Li ^[3] ; Yu,Tian ^[3] ; Feng,Zhao ^[3] ; Ying,Liu ^[5] ; Qihong,Huang ^[3] ; Zhaoyuan,Hou ^[3] ; Fei,Xu ^[5] ; Lei,Shi ^[5] ; Yan,Li ^[3]

作者单位： Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, P.R. China. ^[1] The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116023, P.R. China. ^[2] Institute of Cancer Stem Cell, Dalian Medical University, Dalian, Liaoning 116044, P.R. China. ^[3] Department of Intergrative Medicine, Zhejiang Cancer Hospital, Hangzhou, Zhejiang 310022, P.R. China. ^[4] College of Basic Medical Sciences, Dalian Medical University, Dalian, Liaoning 116044, P.R. China. ^[5]