Down-regulation of microRNA-451a facilitates the activation and proliferation of CD4<sup>+</sup> T cells by targeting Myc in patients with dilated cardiomyopathy.

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作者： Zhipeng,Zeng ^[1] ; Ke,Wang ^[1] ; Yuanyuan,Li ^[1] ; Ni,Xia ^[1] ; Shaofang,Nie ^[1] ; Bingjie,Lv ^[1] ; Min,Zhang ^[1] ; Xin,Tu ^[2] ; Qianqian,Li ^[2] ; Tingting,Tang ^[3] ; Xiang,Cheng ^[4]

作者单位： From the Laboratory of Cardiovascular Immunology, Key Laboratory of Biological Targeted Therapy of the Ministry of Education, Institute of Cardiology, Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, 430022 Wuhan and. ^[1] the Key Laboratory of Molecular Biophysics of the Ministry of Education, Cardio-X Center, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, 430074 Wuhan, China. ^[2] From the Laboratory of Cardiovascular Immunology, Key Laboratory of Biological Targeted Therapy of the Ministry of Education, Institute of Cardiology, Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, 430022 Wuhan and tangtingting@hust.edu.cn. ^[3] From the Laboratory of Cardiovascular Immunology, Key Laboratory of Biological Targeted Therapy of the Ministry of Education, Institute of Cardiology, Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, 430022 Wuhan and nathancx@hust.edu.cn. ^[4]

关键词 Myc (c-Myc)T helper cells cardiovascular disease inflammation microRNA (miRNA)