High impact of methylation accumulation on metachronous gastric cancer: 5-year follow-up of a multicentre prospective cohort study.

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作者： Masahiro,Maeda ^[1] ; Takeshi,Nakajima ^[2] ; Ichiro,Oda ^[3] ; Taichi,Shimazu ^[3] ; Nobutake,Yamamichi ^[4] ; Takao,Maekita ^[5] ; Kiyoshi,Asada ^[6] ; Chizu,Yokoi ^[1] ; Takayuki,Ando ^[3] ; Takeichi,Yoshida ^[7] ; Sohachi,Nanjo ^[1] ; Mitsuhiro,Fujishiro ^[6] ; Takuji,Gotoda ^[1] ; Masao,Ichinose ^[5] ; Toshikazu,Ushijima ^[3]

作者单位： Division of Epigenomics, National Cancer Center Research Institute, Tokyo, Japan. ^[1] Department of Gastrointestinal Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan. ^[2] Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan. ^[3] Prevention Division, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan. ^[4] Department of Gastroenterology, University of Tokyo, Tokyo, Japan. ^[5] Second Department of Internal Medicine, Wakayama Medical University, Wakayama, Japan. ^[6] Department of Gastroenterology and Hepatology, National Center for Global Health and Medicine, Tokyo, Japan. ^[7] Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan. ^[8]

关键词 CANCER SUSCEPTIBILITY GASTRIC CANCER METHYLATION