Key Residues at Third CDR3β Position Impact Structure and Antigen Recognition of Human Invariant NK TCRs.

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作者： Kenji,Chamoto ^[1] ; Tingxi,Guo ^[1] ; Stephen W,Scally ^[2] ; Yuki,Kagoya ^[3] ; Mark,Anczurowski ^[1] ; Chung-Hsi,Wang ^[1] ; Muhammed A,Rahman ^[2] ; Kayoko,Saso ^[1] ; Marcus O,Butler ^[2] ; Priscilla P L,Chiu ^[1] ; Jean-Philippe,Julien ^[1] ; Naoto,Hirano ^[1]

作者单位： Tumor Immunotherapy Program, Campbell Family Institute for Breast Cancer Research, Campbell Family Cancer Research Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario M5G 2M9, Canada. ^[1] Department of Immunology, University of Toronto, Toronto, Ontario M5S 1A8, Canada. ^[2] Program in Molecular Structure and Function, The Hospital for Sick Children Research Institute, Toronto, Ontario M5G 0A4, Canada. ^[3] Department of Medicine, University of Toronto, Toronto, Ontario M5S 1A8, Canada. ^[4] Division of Pediatric Surgery, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada. ^[5] Department of Surgery, University of Toronto, Toronto, Ontario M5S 1A8, Canada; and. ^[6] Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada. ^[7] Tumor Immunotherapy Program, Campbell Family Institute for Breast Cancer Research, Campbell Family Cancer Research Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario M5G 2M9, Canada; naoto.hirano@utoronto.ca. ^[8]