Transcription Factor EB Controls Metabolic Flexibility during Exercise.

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第一作者： Gelsomina,Mansueto

第一单位： Telethon Institute of Genetics and Medicine (TIGEM), Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy.

作者： Gelsomina,Mansueto ^[1] ; Andrea,Armani ^[2] ; Carlo,Viscomi ^[3] ; Luca,D'Orsi ^[1] ; Rossella,De Cegli ^[1] ; Elena V,Polishchuk ^[1] ; Costanza,Lamperti ^[4] ; Ivano,Di Meo ^[4] ; Vanina,Romanello ^[5] ; Silvia,Marchet ^[4] ; Pradip K,Saha ^[6] ; Haihong,Zong ^[7] ; Bert,Blaauw ^[2] ; Francesca,Solagna ^[2] ; Caterina,Tezze ^[2] ; Paolo,Grumati ^[8] ; Paolo,Bonaldo ^[8] ; Jeffrey E,Pessin ^[9] ; Massimo,Zeviani ^[3] ; Marco,Sandri ^[10] ; Andrea,Ballabio ^[11]

作者单位： Telethon Institute of Genetics and Medicine (TIGEM), Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy. ^[1] Department of Biomedical Science, University of Padova, Padova 35121, Italy. ^[2] MRC Mitochondrial Biology Unit, Cambridge CB2 0XY, UK; Fondazione IRCCS Istituto Neurologico "C. Besta," 20133 Milan, Italy. ^[3] Fondazione IRCCS Istituto Neurologico "C. Besta," 20133 Milan, Italy. ^[4] Department of Biomedical Science, University of Padova, Padova 35121, Italy; Venetian Institute of Molecular Medicine, Padova 35129, Italy. ^[5] Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA. ^[6] Hepatobiliary, Pancreatic, and Intestinal Research Institute, North Sichuan Medical College, Nanchong, Sichuan 637000, China; Departments of Medicine and Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY 10461, USA. ^[7] Department of Molecular Medicine, University of Padova, Padova 35121, Italy. ^[8] Departments of Medicine and Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY 10461, USA. ^[9] Telethon Institute of Genetics and Medicine (TIGEM), Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy; Department of Biomedical Science, University of Padova, Padova 35121, Italy; Venetian Institute of Molecular Medicine, Padova 35129, Italy. Electronic address: marco.sandri@unipd.it. ^[10] Telethon Institute of Genetics and Medicine (TIGEM), Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy; Medical Genetics, Department of Pediatrics, Federico II University, Via Pansini 5, 80131 Naples, Italy; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA. Electronic address: ballabio@tigem.it. ^[11]

关键词 PGC1alpha TFEB autophagy diabetes exercise glucose insulin metabolic flexibility mitochondria mitochondrial fusion