Pink1/Parkin-mediated mitophagy play a protective role in cisplatin induced renal tubular epithelial cells injury.

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作者： Chuanyan,Zhao ^[1] ; Zhuyun,Chen ^[1] ; Xueqiang,Xu ^[1] ; Xiaofei,An ^[2] ; Suyan,Duan ^[1] ; Zhimin,Huang ^[1] ; Chengning,Zhang ^[1] ; Lin,Wu ^[1] ; Bo,Zhang ^[1] ; Aihua,Zhang ^[3] ; Changying,Xing ^[4] ; Yanggang,Yuan ^[5]

作者单位： Department of Nephrology, the First Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, China. ^[1] Department of Endocrinology, Jiangsu Province Hospital of Chinese Medicine, Nanjing, China. ^[2] Department of Nephrology, Nanjing Children's Hospital, Nanjing Medical University, Nanjing, China; Institute of Pediatrics, Nanjing Medical University, Nanjing, China. ^[3] Department of Nephrology, the First Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, China. Electronic address: cyxing62@126.com. ^[4] Department of Nephrology, the First Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, China. Electronic address: ygyuan@njmu.edu.cn. ^[5]

关键词 AKI Cisplatin Mitochondrial dysfunction Mitophagy Parkin Pink1

主题词顺铂(Cisplatin);上皮细胞(Epithelial Cells);人类(Humans);肾小管(Kidney Tubules);蛋白激酶类(Protein Kinases);泛素蛋白连接酶类(Ubiquitin-Protein Ligases)

DOI 10.1016/j.yexcr.2016.12.015

PMID 28024839

发布时间 2019-12-10

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