首页> American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons> Early Conversion From Calcineurin Inhibitor- to Everolimus-Based Therapy Following Kidney Transplantation: Results of the Randomized ELEVATE Trial.

Early Conversion From Calcineurin Inhibitor- to Everolimus-Based Therapy Following Kidney Transplantation: Results of the Randomized ELEVATE Trial.

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第一作者： J W,de Fijter

第一单位： Department of Nephrology, Leiden University Medical Center, Leiden, the Netherlands.

作者： J W,de Fijter ^[1] ; H,Holdaas ^[2] ; O,Øyen ^[3] ; J-S,Sanders ^[4] ; S,Sundar ^[5] ; F J,Bemelman ^[6] ; C,Sommerer ^[7] ; J,Pascual ^[8] ; Y,Avihingsanon ^[9] ; C,Pongskul ^[10] ; F,Oppenheimer ^[11] ; L,Toselli ^[12] ; G,Russ ^[13] ; Z,Wang ^[14] ; P,Lopez ^[15] ; J,Kochuparampil ^[15] ; J M,Cruzado ^[16] ; M,van der Giet ^[17] ; ELEVATE Study Group

作者单位： Department of Nephrology, Leiden University Medical Center, Leiden, the Netherlands. ^[1] Section of Nephrology, Department of Transplant Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway. ^[2] Section of Transplant Surgery, Department of Transplant Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway. ^[3] Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. ^[4] Department of Nephrology, Columbia Asia Hospitals, Malleshwaram West, Bangalore, India. ^[5] Department of Nephrology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands. ^[6] Department of Nephrology, Heidelberg University Hospital, Heidelberg, Germany. ^[7] Department of Nephrology, Hospital del Mar, Barcelona, Spain. ^[8] Faculty of Medicine, Chulalongkorn University and Excellent Center of Organ Transplantation, King Chulalongkorn Memorial Hospital, Patumwan, Bangkok, Thailand. ^[9] Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand. ^[10] Department of Nephrology and Kidney Transplantation, Hospital Clínic de Barcelona, Barcelona, Spain. ^[11] Kidney, Liver and Pancreas Transplant Unit, CRAI Norte, Ministry of Health, Buenos Aires, Argentina. ^[12] University of Adelaide and Central and Northern Adelaide Renal and Transplant Service, Royal Adelaide Hospital, North Terrace, Adelaide, Australia. ^[13] Biometrics and Statistical Science, Novartis Pharmaceuticals, East Hanover, NJ. ^[14] Research and Development, Novartis Pharma AG, Basel, Switzerland. ^[15] Department of Nephrology, University Hospital of Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain. ^[16] Department of Nephrology, Charité - Universitätsmedizin, Berlin, Germany. ^[17]

关键词 calcineurin inhibitor (CNI)cardiovascular disease clinical research/practice clinical trial immunosuppressant immunosuppression/immune modulation kidney (allograft) function/dysfunction kidney transplantation/nephrology mechanistic target of rapamycin: everolimus