Prenatal stress affects placental cytokines and neurotrophins, commensal microbes, and anxiety-like behavior in adult female offspring.

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作者： Tamar L,Gur ^[1] ; Lena,Shay ^[2] ; Aditi Vadodkar,Palkar ^[3] ; Sydney,Fisher ^[4] ; Vanessa A,Varaljay ^[5] ; Scot,Dowd ^[6] ; Michael T,Bailey ^[7]

作者单位： Department of Psychiatry & Behavioral Health, Wexner Medical Center at The Ohio State University, United States; Department of Neuroscience, Wexner Medical Center at The Ohio State University, United States; Department of Obstetrics & Gynecology, Wexner Medical Center at The Ohio State University, United States; Institute for Behavioral Medicine Research, Wexner Medical Center at The Ohio State University, United States. Electronic address: tamar.gur@osumc.edu. ^[1] Department of Psychiatry & Behavioral Health, Wexner Medical Center at The Ohio State University, United States. ^[2] Department of Psychiatry & Behavioral Health, Wexner Medical Center at The Ohio State University, United States; Institute for Behavioral Medicine Research, Wexner Medical Center at The Ohio State University, United States. ^[3] Department of Psychiatry & Behavioral Health, Wexner Medical Center at The Ohio State University, United States; Institute for Behavioral Medicine Research, Wexner Medical Center at The Ohio State University, United States; Center for Microbial Pathogenesis, The Research Institute, Nationwide Children's Hospital, The Ohio State University, United States. ^[4] Center for Microbial Pathogenesis, The Research Institute, Nationwide Children's Hospital, The Ohio State University, United States; Biosciences Division, College of Dentistry, The Ohio State University, United States; Department of Pediatrics, Wexner Medical Center at The Ohio State University, United States. ^[5] Research and Testing Laboratory and Medical Biofilm Research Institute, Lubbock, TX 79407, United States. ^[6] Institute for Behavioral Medicine Research, Wexner Medical Center at The Ohio State University, United States; Center for Microbial Pathogenesis, The Research Institute, Nationwide Children's Hospital, The Ohio State University, United States; Biosciences Division, College of Dentistry, The Ohio State University, United States; Department of Pediatrics, Wexner Medical Center at The Ohio State University, United States. ^[7]

关键词 Anxiety-like behavior Gut–brain axis Microbiota Placenta Prenatal stress