Imbalance properties of centre-stratified permuted-block and complete randomisation for several treatments in a clinical trial.

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作者： Vladimir V,Anisimov ^[1] ; Wai Y,Yeung ^[2] ; D Stephen,Coad ^[3]

作者单位： School of Mathematics and Statistics, University of Glasgow, 15 University Gardens, Glasgow, G12 8QW, U.K. ^[1] Roche Products Limited, 6 Falcon Way, Shire Park, Welwyn Garden City, AL7 1TW, U.K. ^[2] School of Mathematical Sciences, Queen Mary University of London, Mile End Road, London, E1 4NS, U.K. ^[3]

关键词 Poisson-gamma model covariance multicentre clinical trial multivariate normal distribution power simulation

主题词人类(Humans);模型, 统计学(Models, Statistical);病人遴选(Patient Selection);泊松分布(Poisson Distribution);随机分配(Random Allocation);随机对照试验(主题)(Randomized Controlled Trials as Topic);统计学(主题)(Statistics as Topic)

DOI 10.1002/sim.7206

PMID 28028825

发布时间 2018-05-15

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