Third-generation CD28/4-1BB chimeric antigen receptor T cells for chemotherapy relapsed or refractory acute lymphoblastic leukaemia: a non-randomised, open-label phase I trial protocol.

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作者： Xiao-Yi,Tang ^[1] ; Yao,Sun ^[1] ; Ang,Zhang ^[1] ; Guo-Liang,Hu ^[1] ; Wei,Cao ^[1] ; Dan-Hong,Wang ^[2] ; Bin,Zhang ^[1] ; Hu,Chen ^[2]

作者单位： Cell and Gene Therapy Center, Academy of Military Medical Sciences, Beijing, China. ^[1] Department of Hematopoietic Stem Cell Transplantation, Affiliated Hospital of Academy of Military Medical Sciences, Beijing, China. ^[2]

关键词 IMMUNOLOGY Third-generation acute lymphoblastic leukemia chimeric antigen receptor

主题词成年人(Adult);细胞系, 肿瘤(Cell Line, Tumor);临床方案(Clinical Protocols);女(雌)性(Female);人类(Humans);免疫疗法, 过继(Immunotherapy, Adoptive);白细胞, 单核(Leukocytes, Mononuclear);淋巴细胞活化(Lymphocyte Activation);男(雄)性(Male);中年人(Middle Aged);前体细胞淋巴母细胞白血病淋巴瘤(Precursor Cell Lymphoblastic Leukemia-Lymphoma);受体, 抗原, T细胞(Receptors, Antigen, T-Cell);复发(Recurrence);缓解诱导(Remission Induction)

DOI 10.1136/bmjopen-2016-013904

PMID 28039295

发布时间 2019-02-02

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BMJ open

2016年6卷12期

e013904页

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Third-generation CD28/4-1BB chimeric antigen receptor T cells for chemotherapy relapsed or refractory acute lymphoblastic leukaemia: a non-randomised, open-label phase I trial protocol.

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BMJ open

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Third-generation CD28/4-1BB chimeric antigen receptor T cells for chemotherapy relapsed or refractory acute lymphoblastic leukaemia: a non-randomised, open-label phase I trial protocol.

BMJ open

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BMJ open

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