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Novel chimeric virus-like particles vaccine displaying MERS-CoV receptor-binding domain induce specific humoral and cellular immune response in mice.

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作者: Chong,Wang [1] ; Xuexing,Zheng [2] ; Weiwei,Gai [3] ; Gary,Wong [4] ; Hualei,Wang [5] ; Hongli,Jin [6] ; Na,Feng [5] ; Yongkun,Zhao [5] ; Weijiao,Zhang [3] ; Nan,Li [6] ; Guoxing,Zhao [6] ; Junfu,Li [4] ; Jinghua,Yan [4] ; Yuwei,Gao [5] ; Guixue,Hu [7] ; Songtao,Yang [8] ; Xianzhu,Xia [9]
作者单位: Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Institute of Military Veterinary, Academy of Military Medical Sciences, Changchun, China; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China. [1] School of Public Health, Shandong University, Jinan, China. [2] Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Institute of Military Veterinary, Academy of Military Medical Sciences, Changchun, China; College of Veterinary Medicine, Jilin University, Changchun, China. [3] CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China. [4] Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Institute of Military Veterinary, Academy of Military Medical Sciences, Changchun, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, China. [5] Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Institute of Military Veterinary, Academy of Military Medical Sciences, Changchun, China. [6] College of Animal Science and Technology, Jilin Agricultural University, Changchun, China. [7] Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Institute of Military Veterinary, Academy of Military Medical Sciences, Changchun, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, China. Electronic address: yst62041@163.com. [8] Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Institute of Military Veterinary, Academy of Military Medical Sciences, Changchun, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, China. Electronic address: xiaxzh@cae.cn. [9]
DOI 10.1016/j.antiviral.2016.12.019
PMID 28040513
发布时间 2020-04-07
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