Lipid Desaturation Is a Metabolic Marker and Therapeutic Target of Ovarian Cancer Stem Cells.

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作者： Junjie,Li ^[1] ; Salvatore,Condello ^[2] ; Jessica,Thomes-Pepin ^[3] ; Xiaoxiao,Ma ^[4] ; Yu,Xia ^[4] ; Thomas D,Hurley ^[5] ; Daniela,Matei ^[6] ; Ji-Xin,Cheng ^[7]

作者单位： Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA. ^[1] Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. ^[2] Department of Obstetrics and Gynecology, Indiana University, Indianapolis, IN 46202, USA. ^[3] Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA. ^[4] Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Indiana University Simon Cancer Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA. ^[5] Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA; Jesse Brown VA Medical Center, Chicago, IL 60612, USA; Robert H. Lurie Comprehensive Cancer Center, Chicago, IL 60611, USA. Electronic address: daniela.matei@northwestern.edu. ^[6] Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA; Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA; Purdue University Center for Cancer Research, Purdue University, West Lafayette, IN 47907, USA. Electronic address: jcheng@purdue.edu. ^[7]

关键词 NF-κB Raman spectroscopic imaging SCD1 cancer stem cells lipid desaturation ovarian cancer