Endonuclease EEPD1 Is a Gatekeeper for Repair of Stressed Replication Forks.

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作者： Hyun-Suk,Kim ^[1] ; Jac A,Nickoloff ^[2] ; Yuehan,Wu ^[3] ; Elizabeth A,Williamson ^[3] ; Gurjit Singh,Sidhu ^[3] ; Brian L,Reinert ^[3] ; Aruna S,Jaiswal ^[3] ; Gayathri,Srinivasan ^[3] ; Bhavita,Patel ^[3] ; Kimi,Kong ^[3] ; Sandeep,Burma ^[4] ; Suk-Hee,Lee ^[5] ; Robert A,Hromas ^[6]

作者单位： From the Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana 46202. ^[1] the Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, Colorado 80523. ^[2] the Department of Medicine and the Cancer Center, University of Florida Health, Gainesville, Florida 32610, and. ^[3] the Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas 75390. ^[4] From the Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana 46202, slee@iupui.edu. ^[5] the Department of Medicine and the Cancer Center, University of Florida Health, Gainesville, Florida 32610, and robert.hromas@medicine.ufl.edu. ^[6]

关键词 DNA damage DNA endonuclease DNA repair DNA replication end resection homologous recombination nuclease replication fork stress

主题词 DNA修复(DNA Repair);DNA复制(DNA Replication);内切脱氧核糖核酸酶类(Endodeoxyribonucleases);HEK293细胞(HEK293 Cells);人类(Humans)

DOI 10.1074/jbc.M116.758235

PMID 28049724

发布时间 2021-02-05

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