COX-2/mPGES-1/PGE2 cascade activation mediates uric acid-induced mesangial cell proliferation.-论文-万方医学网

第一作者： Shuzhen,Li

第一单位： Department of Nephrology, Children's Hospital of Nanjing Medical University, Nanjing 210008, China.

作者： Shuzhen,Li ^[1] ; Zhenzhen,Sun ^[2] ; Yue,Zhang ^[3] ; Yuan,Ruan ^[1] ; Qiuxia,Chen ^[2] ; Wei,Gong ^[3] ; Jing,Yu ^[1] ; Weiwei,Xia ^[2] ; John Ci-Jiang,He ^[3] ; Songming,Huang ^[4] ; Aihua,Zhang ^[1] ; Guixia,Ding ^[2] ; Zhanjun,Jia ^[3]

作者单位： Department of Nephrology, Children's Hospital of Nanjing Medical University, Nanjing 210008, China. ^[1] Jiangsu Key Laboratory of Pediatrics, Nanjing Medical University, Nanjing 210029, China. ^[2] Nanjing Key Laboratory of Pediatrics, Children's Hospital of Nanjing Medical University, Nanjing 210008, China. ^[3] Department of Endocrinology, Jiangsu Province Hospital of TCM, Affiliated Hospital of Nanjing University of TCM, Nanjing 210008, China. ^[4] Division of Nephrology, Department of Medicine, Mount Sinai School of Medicine, New York, NY 210029, USA. ^[5]

主题词老年人(Aged);动物(Animals);病例对照研究(Case-Control Studies);细胞系(Cell Line);细胞增殖(Cell Proliferation);细胞周期蛋白A2(Cyclin A2);细胞周期蛋白D1(Cyclin D1);环氧化酶2(Cyclooxygenase 2);环氧化酶2抑制剂(Cyclooxygenase 2 Inhibitors);地诺前列酮(Dinoprostone);剂量效应关系, 药物(Dose-Response Relationship, Drug);女(雌)性(Female);痛风(Gout);人类(Humans);高尿酸血症(Hyperuricemia);男(雄)性(Male);肾小球系膜细胞(Mesangial Cells);小鼠(Mice);中年人(Middle Aged);RNA干扰(RNA Interference);信号传导(Signal Transduction);时间因素(Time Factors);转染(Transfection);尿酸(Uric Acid)

DOI 10.18632/oncotarget.14363

PMID 28052039

发布时间 2018-11-13

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COX-2/mPGES-1/PGE2 cascade activation mediates uric acid-induced mesangial cell proliferation.

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COX-2/mPGES-1/PGE2 cascade activation mediates uric acid-induced mesangial cell proliferation.

Oncotarget

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Oncotarget

相关期刊

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