Conformational Freedom of the LRP6 Ectodomain Is Regulated by N-glycosylation and the Binding of the Wnt Antagonist Dkk1.
第一作者:
Kyoko,Matoba
第一单位:
Laboratory of Protein Synthesis and Expression, Institute for Protein Research, Osaka University, Osaka 565-0871, Japan.
作者:
主题词
细胞膜(Cell Membrane);保守序列(Conserved Sequence);冷冻电子显微镜检查(Cryoelectron Microscopy);糖基化(Glycosylation);人类(Humans);胞间信号肽类和蛋白质类(Intercellular Signaling Peptides and Proteins);模型, 分子(Models, Molecular);突变蛋白质类(Mutant Proteins);突变(Mutation);负染色(Negative Staining);多糖类(Polysaccharides);蛋白质结合(Protein Binding);蛋白质构象(Protein Conformation);蛋白质多聚化(Protein Multimerization);构效关系(Structure-Activity Relationship);Wnt蛋白质类(Wnt Proteins)
DOI
10.1016/j.celrep.2016.12.017
PMID
28052259
发布时间
2023-01-08
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Cell reports
32-40页
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