Comprehensive Genomic Analysis of Metastatic Mucinous Urethral Adenocarcinoma Guides Precision Oncology Treatment: Targetable EGFR Amplification Leading to Successful Treatment With Erlotinib.

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第一作者： Alan H,Bryce

第一单位： Division of Hematology/Oncology, Mayo Clinic, Phoenix, AZ; Mayo Clinic Cancer Center, Phoenix, AZ; Center for Individualized Medicine, Mayo Clinic, Rochester, MN. Electronic address: bryce.alan@mayo.edu.

作者： Alan H,Bryce ^[1] ; Mitesh J,Borad ^[2] ; Jan B,Egan ^[3] ; Rachel M,Condjella ^[4] ; Winnie S,Liang ^[5] ; Rafael,Fonseca ^[2] ; Ann E,McCullough ^[6] ; Katherine S,Hunt ^[7] ; Nicole R,Ritacca ^[4] ; Michael T,Barrett ^[8] ; Maitray D,Patel ^[9] ; Scott W,Young ^[9] ; Alvin C,Silva ^[9] ; Thai H,Ho ^[2] ; Thorvardur R,Halfdanarson ^[2] ; Melissa L,Stanton ^[6] ; John,Cheville ^[10] ; Scott,Swanson ^[11] ; Daniel E,Schneider ^[11] ; Robert R,McWilliams ^[12] ; Angela,Baker ^[5] ; Jessica,Aldrich ^[5] ; Ahmet,Kurdoglu ^[5] ; Tyler,Izatt ^[5] ; Alexis,Christoforides ^[5] ; Irene,Cherni ^[5] ; Sara,Nasser ^[5] ; Rebecca,Reiman ^[5] ; Lori,Cuyugan ^[5] ; Jacquelyn,McDonald ^[5] ; Jonathan,Adkins ^[5] ; Stephen D,Mastrian ^[5] ; Daniel D,Von Hoff ^[5] ; David W,Craig ^[5] ; A Keith,Stewart ^[2] ; John D,Carpten ^[5]

作者单位： Division of Hematology/Oncology, Mayo Clinic, Phoenix, AZ; Mayo Clinic Cancer Center, Phoenix, AZ; Center for Individualized Medicine, Mayo Clinic, Rochester, MN. Electronic address: bryce.alan@mayo.edu. ^[1] Division of Hematology/Oncology, Mayo Clinic, Phoenix, AZ; Mayo Clinic Cancer Center, Phoenix, AZ; Center for Individualized Medicine, Mayo Clinic, Rochester, MN. ^[2] Center for Individualized Medicine, Mayo Clinic, Rochester, MN. ^[3] Mayo Clinic Cancer Center, Phoenix, AZ. ^[4] Translational Genomics Research Institute, Phoenix, AZ. ^[5] Department of Laboratory Medicine and Pathology, Mayo Clinic, Scottsdale, AZ. ^[6] Division of Hematology/Oncology, Mayo Clinic, Phoenix, AZ. ^[7] Mayo Clinic Cancer Center, Phoenix, AZ; Translational Genomics Research Institute, Phoenix, AZ. ^[8] Department of Radiology, Mayo Clinic, Scottsdale, AZ. ^[9] Department of Anatomic and Clinical Pathology, Mayo Clinic, Rochester, MN. ^[10] Department of Urology, Mayo Clinic, Phoenix, AZ. ^[11] Center for Individualized Medicine, Mayo Clinic, Rochester, MN; Mayo Clinic Cancer Center, Rochester, MN. ^[12]

关键词 EGFR Exome Genome Transcriptome Urethral adenocarcinoma