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Activating mutations and translocations in the guanine exchange factor VAV1 in peripheral T-cell lymphomas.

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第一作者： Francesco,Abate

第一单位： Department of Systems Biology, Columbia University Medical Center, New York, NY 10032.

作者： Francesco,Abate ^[1] ; Ana C,da Silva-Almeida ^[2] ; Sakellarios,Zairis ^[1] ; Javier,Robles-Valero ^[3] ; Lucile,Couronne ^[4] ; Hossein,Khiabanian ^[1] ; S Aidan,Quinn ^[2] ; Mi-Yeon,Kim ^[2] ; Maria Antonella,Laginestra ^[5] ; Christine,Kim ^[2] ; Danilo,Fiore ^[6] ; Govind,Bhagat ^[7] ; Miguel Angel,Piris ^[8] ; Elias,Campo ^[9] ; Izidore S,Lossos ^[10] ; Olivier A,Bernard ^[11] ; Giorgio,Inghirami ^[6] ; Stefano,Pileri ^[5] ; Xosé R,Bustelo ^[12] ; Raul,Rabadan ^[13] ; Adolfo A,Ferrando ^[14] ; Teresa,Palomero ^[15]

作者单位： Department of Systems Biology, Columbia University Medical Center, New York, NY 10032. ^[1] Institute for Cancer Genetics, Columbia University, New York, NY 10032. ^[2] Centro de Investigación del Cáncer, Consejo Superior de Investigaciones Científicas-University of Salamanca, 37007 Salamanca, Spain. ^[3] Department of Adult Hematology, Necker Hospital, 75015 Paris, France.;INSERM UMR163, Centre National de la Recherche Scientifique Équipe de Recherche Labellisée 8254, Institut Imagine, 75015 Paris, France.;Paris Descartes University, 75006 Paris, France. ^[4] Hemopathology Unit, European Institute of Oncology, 20139 Milan, Italy. ^[5] Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10065. ^[6] Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY 10032. ^[7] Instituto de Formación e Investigación, Hospital Universitario Marqués de Valdecilla, 39008 Santander, Spain. ^[8] Department of Pathology, Hospital Clinic, 08036 Barcelona, Spain. ^[9] Division of Hematology-Oncology, Sylvester Comprehensive Cancer Center, Miami, FL 33136.;Department of Molecular and Cellular Pharmacology, University of Miami, Miami, FL 33101. ^[10] INSERM U1170, 94805 Villejuif, France.;Université Paris-Sud, 91405 Orsay, France.;Gustave Roussy, 94805 Villejuif, France. ^[11] Centro de Investigación del Cáncer, Consejo Superior de Investigaciones Científicas-University of Salamanca, 37007 Salamanca, Spain.;Centro de Investigacion Biomedica en Red de Cancer (CIBERONC), Spain. ^[12] Department of Systems Biology, Columbia University Medical Center, New York, NY 10032; rr2579@cumc.columbia.edu af2196@columbia.edu tp2151@columbia.edu.;Department of Biomedical Informatics, Columbia University Medical Center, New York, NY 10032. ^[13] Institute for Cancer Genetics, Columbia University, New York, NY 10032; rr2579@cumc.columbia.edu af2196@columbia.edu tp2151@columbia.edu.;Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY 10032.;Department of Pediatrics, Columbia University Medical Center, New York, NY 10032. ^[14] Institute for Cancer Genetics, Columbia University, New York, NY 10032; rr2579@cumc.columbia.edu af2196@columbia.edu tp2151@columbia.edu.;Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY 10032. ^[15]

关键词 VAV1 gene fusion mutation peripheral T-cell lymphoma