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Glioblastoma on a microfluidic chip: Generating pseudopalisades and enhancing aggressiveness through blood vessel obstruction events.

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第一作者： Jose M,Ayuso

第一单位： Group of Applied Mechanics and Bioengineering. Centro Investigación Biomédica en Red. Bioingenieria, Biomateriales y Nanomedicina (CIBER-BBN), Zaragoza, Spain.;Aragón Institute of Engineering Research (I3A), University of Zaragoza, Zaragoza, Spain.;Aragon Institute of Biomedical Research, Instituto de Salud Carlos III, Zaragoza, Spain.

作者： Jose M,Ayuso ^[1] ; Rosa,Monge ^[1] ; Alicia,Martínez-González ^[2] ; María,Virumbrales-Muñoz ^[1] ; Guillermo A,Llamazares ^[1] ; Javier,Berganzo ^[3] ; Aurelio,Hernández-Laín ^[4] ; Jorge,Santolaria ^[5] ; Manuel,Doblaré ^[1] ; Christopher,Hubert ^[6] ; Jeremy N,Rich ^[6] ; Pilar,Sánchez-Gómez ^[7] ; Víctor M,Pérez-García ^[2] ; Ignacio,Ochoa ^[1] ; Luis J,Fernández ^[1]

作者单位： Group of Applied Mechanics and Bioengineering. Centro Investigación Biomédica en Red. Bioingenieria, Biomateriales y Nanomedicina (CIBER-BBN), Zaragoza, Spain.;Aragón Institute of Engineering Research (I3A), University of Zaragoza, Zaragoza, Spain.;Aragon Institute of Biomedical Research, Instituto de Salud Carlos III, Zaragoza, Spain. ^[1] Institute of Applied Mathematics in Science and Engineering, Castilla-La Mancha University, Ciudad-Real, Spain. ^[2] MEMS/MST Department, Ikerlan S. Coop., Mondragón, Spain. ^[3] Department of Pathology (Neuropathology), Hospital Universitario 12 de Octubre Research Institute, Madrid, Spain. ^[4] Department of Design and Manufacturing Engineering, University of Zaragoza, Zaragoza, Spain. ^[5] Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA. ^[6] Neuro-oncology Unit, Health Institute Carlos III-UFIEC, Madrid, Spain. ^[7]

关键词 SU-8 glioblastoma microfluidics migration pseudopalisades